SARS-CoV-2 has been circulating in northeastern Brazil since February 2020: evidence for antibody detection in asymptomatic patients - 25/04/21
Doi : 10.1016/j.jinf.2020.11.037
Ricardo Queiroz Gurgel a, Laís Catarine de Sá b, Daniela Raguer Valadão Souza c, Aline Fagundes Martins c, Igor Leonardo Santos Matos d, Alexandra Giovanna Aragão Lima b, Sarah Cristina Fontes Vieira a, José Melquiades de Rezende Neto c, Luis Eduardo Cuevas e, Lysandro Pinto Borges d, ⁎ 
a Department of Medicine, Federal, Post-Graduate Programs in Parasitic Biology and Health Sciences, Federal University of Sergipe, Aracaju, Sergipe, Brazil
b Post-Graduate Program in Parasitic Biology, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil
c Department of Education in Health, Federal University of Sergipe, Lagarto, Sergipe, Brazil
d Department of Pharmacy and Clinical Analysis, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil
e Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
⁎Corresponding author.
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Highlights |
• | COVID-19 clinical cases were reported in Brazil in February 2020. |
• | SARS-CoV-2 may have circulated before the clinical cases were detected. |
• | We tested serum samples collected in Jan-April 2020 for SARS-CoV-2 antibodies. |
• | 16/989 (1.6%) had antibodies, suggesting an earlier circulation of the virus. |
• | Patients with undetected and reported infection had similar age, sex and residency. |
Abstract |
We screened stored samples collected before COVID-19 had been reported in Brazil. 989 samples were tested for SAR-CoV-2 antibodies using two different methods; 16 (1.6%) were positive (7 (43.8%) IgM, 3 (18.8%) IgG and 6 (37.5%) IgG/IgM positive), suggesting SARS-CoV-2 had circulated before the first reported COVID-19 case in Brazil.
Le texte complet de cet article est disponible en PDF.© 2020
The British Infection Association. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 82 - N° 5
P. 186-230 - mai 2021 Retour au numéro
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