Low impact of SARS-CoV-2 infection among paediatric acute respiratory disease hospitalizations - 18/03/21
on behalf of
Kids-Corona Paediatric Hospitalist group1
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Highlights |
• | Most of the episodes of acute lower-respiratory diseases were not related to SARS-CoV-2 infection. |
• | Human-rhinovirus/enterovirus was the main detection during the pandemics. |
• | SARS-CoV-2 was mainly found causing pneumonia in older children. |
• | Bronchiolitis is possible, but SARS-CoV-2 was found causing a minority of these respiratory episodes. |
• | Clinicians should be aware that SARS-CoV-2 infection could be the agent of lower-respiratory disease in paediatric patients with lymphopenia. |
Summary |
Objective |
This study describes the characteristics of children requiring admission with an acute lower-respiratory disease (ALRD) during the SARS-CoV-2 pandemics.
Methods |
Epidemiological, clinical, and microbiological data from patients with ALRD (pneumonia, bronchiolitis, bronchospasm) admitted to a reference paediatric hospital in Spain during the pandemic peak (week 11–20/2020) were prospectively analysed.
Results |
110 patients were included. 7 were SARS-CoV-2(+) and they were older in comparison to SARS-CoV-2(-). Among SARS-CoV-2(+) patients, pneumonia was the main clinical diagnosis (6/7) and bronchospasm was absent. Only 1 of 29 infants diagnosed with bronchiolitis was SARS-CoV-2(+). Lower values of leucocytes, lymphocytes, neutrophils, and platelets and higher values of creatinine were found in SARS-CoV-2(+).
Human-rhinovirus/enterovirus was the main detection (11/32). There were not differences in PICU admission rates between SARS-CoV-2(+) and (-).
Conclusions |
Most of the ALRD episodes identified during the pandemics were not related to SARS-CoV-2 infection. SARS-CoV-2 was mainly found causing pneumonia in older children.
Le texte complet de cet article est disponible en PDF.Keywords : SARS-CoV-2, COVID-19, Bronchiolitis, Pneumonia, Respiratory viral infections
Plan
Vol 82 - N° 3
P. 414-451 - mars 2021 Retour au numéro
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