Thromboelastometry-guided anticoagulation reversal in a patient with ventricular assist device with intracranial hemorrhage - 24/02/21
, Josue Portillo, DO b , Lydia Sharp, MD b , Megan A. Rech, PharmD, MS, b Abstract |
Intracranial hemorrhage (ICH) is a known complication in patients with ventricular assist devices (VAD). We present a case of a 42-year-old male with a VAD and on warfarin who presented to the emergency department with ICH necessitating anticoagulant reversal. An attenuated dose of 15 units/kg of 4-factor prothrombin complex-concentrates (4F-PCC) was given and the patient’s coagulation profile was subsequently assessed using rotational thromboelastometry (ROTEM®) to determine appropriateness of reversal. ROTEM® analysis showed adequate reversal at the time of assessment and the patient ultimately returned home without further functional deficits, highlighting the role of ROTEM® to guide anticoagulation reversal in the VAD patient population.
Le texte complet de cet article est disponible en PDF.Keywords : Ventricular assist device (VAD), 4-factor prothrombin-complex-concentrates (4F-PCC), Rotational thromboelastometry (ROTEM®), Intracranial hemorrhage (ICH)
Plan
Vol 41
P. 265.e5-265.e8 - mars 2021 Retour au numéro
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