Surgical procedures for the treatment of epilepsy and brain tumors can involve resection of regions closed or merged to functionally eloquent cortical areas. Removal of language, primary motor, or sensory areas can be associated with transient or permanent functional deficits, which should be avoided if possible. Functional electrical cortical stimulation is a reliable technique to prevent or minimize motor, sensory and language deficits and has been used in humans since the 1950s to identify functional cortex, and it can also localize epileptogenic regions. This article discusses functional electrical stimulation in adults and children for different functional modalities.