Puberty Is Associated with a Rising Hemoglobin A1c, Even in Youth with Normal Weight - 22/02/21
Doi : 10.1016/j.jpeds.2020.10.044
Megan M. Kelsey, MD 1, ⁎ 
, Cameron Severn, MS 1, 2, Allison M. Hilkin, BS 1, Laura Pyle, PhD 1, 2, Kristen J. Nadeau, MD, MS 1, Philip S. Zeitler, MD, PhD 1
, Cameron Severn, MS 1, 2, Allison M. Hilkin, BS 1, Laura Pyle, PhD 1, 2, Kristen J. Nadeau, MD, MS 1, Philip S. Zeitler, MD, PhD 1 1 Department of Pediatrics, University of Colorado Denver School of Medicine, Aurora, CO
2 Department of Biostatistics, University of Colorado Denver School of Medicine, Aurora, CO
∗Reprint requests: Megan M. Kelsey, MD, MS, Department of Pediatrics, University of Colorado Denver School of Medicine, 13123 E 16th Ave, B265, Aurora, CO 80045Department of Pediatrics, University of Colorado Denver School of Medicine13123 E 16th Ave, B265AuroraCO80045
Abstract |
Our objective was to explore the longitudinal trajectory of hemoglobin A1c (HbA1c) in well-characterized youth (n = 84) with normal weight and obesity during puberty. HbA1c rose from early puberty to Tanner stage 5, even in healthy, normal weight youth, revealing important implications for defining normal glycemia and prediabetes in adolescents.
Le texte complet de cet article est disponible en PDF.Abbreviations : BMI, DI, HbA1c, HIP, T2D, T5
Plan
| The Health Influence of Puberty (HIP) Study was sponsored by the following grants: American Diabetes Association Junior Faculty Award (1-11-JF-23), Children’s Hospital Colorado Research Institute Research Scholar Award, Building Interdisciplinary Research Careers in Women’s Health National Institutes of Health/National Institute of Child Health and Human Development BIRCWH K12 (HD057022-06), National Institutes of Health/National Center for Advancing Translational Sciences Colorado CTSA UL1 TR001082, Nutrition and Obesity Research Center Pilot Award National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases DK048520-13, Children’s Hospital Colorado Research Institute Bridge Award, University of Colorado School of Medicine Dean’s Bridge Award. The authors declare no conflicts of interest. |
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| Portions of this study were presented at the virtual American Diabetes Association Meeting, June 12-16, 2020. |
© 2020
Elsevier Inc. Tous droits réservés.
Vol 230
P. 244-247 - mars 2021 Retour au numéro
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