Tobacco use as a well-recognized cause of severe COVID-19 manifestations - 12/02/21
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Abstract |
Introduction |
The Coronavirus disease (COVID-19) infection is caused by the novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) primarily affecting the lungs. All tobacco-related illnesses including asthma, chronic obstructive pulmonary disease (COPD), and coronary artery disease are known to reduce the lung capacity and impair the immune system of the body and can greatly influence the ability to fight the novel coronavirus. The purpose of this state-of-the-art literature review is to summarize the evidence of the association of tobacco use with the severity of the COVID-19 manifestations.
Method |
Articles describing the association of tobacco use with the severity of COVID-19 manifestations were searched on PubMed, MEDLINE, and Google. This review covers the relevant studies on the subject published from January 1, 2020 to September 10, 2020.
Results |
Tobacco use in all forms, whether smoking or chewing, is significantly associated with severe COVID-19 outcomes. Pre-existing comorbidities in tobacco users such as cardiovascular diseases, diabetes, respiratory diseases and hypertension were found to further aggravate the disease manifestations making the treatment of such COVID-19 patients more challenging due to their rapid clinical deterioration.
Conclusions |
Current review indicates that nicotine exposure is linked to cardiopulmonary vulnerability to COVID-19 and tobacco use can be a potential risk factor for not only getting the viral infection but also its severe manifestations. The current pandemic provides a teachable moment to break the cycle of nicotine addiction and accelerate national tobacco control programs to achieve a tobacco-free world.
Le texte complet de cet article est disponible en PDF.Highlights |
• | Tobacco use/Smoking is a potential risk factor for COVID-19 infection with severe manifestations. |
• | Tobacco users with pre-existing comorbidities of the heart or lungs are at higher risk. |
• | Tobacco cessation reduces the COVID-19 infection by downregulation of ACE2 levels. |
• | Current pandemic could be the best time to break the cycle of nicotine addiction. |
Keywords : Tobacco use, COVID-19, ACE-2, Severity, Cessation
Plan
Vol 176
Article 106233- janvier 2021 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.