Leslie Naesens, MD a, b, Julie Smet, MD c, Simon J. Tavernier, MD, PhD a, d, Petra Schelstraete, MD, PhD e, Levi Hoste, MD a, e, Stijn Lambrecht, PhD f, Helene Verhelst, MD, PhD g, Jutte van der Werff ten Bosch, MD, PhD h, Alina Ferster, MD, PhD i, Sophie Blumental, MD i, Pascale Hilbert, PhD j, Tessa Kerre, MD, PhD b, Johan Vande Walle, MD, PhD k, Christoph Licht, MD l, Lubka T. Roumenina, PhD m, Patrick Stordeur, PhD c, ∗
These authors contributed equally to this work.
, Filomeen Haerynck, MD, PhD a, e, ∗
These authors contributed equally to this work.
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a Primary Immunodeficiency Research Lab, Center for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Center, Ghent University Hospital, Ghent, Belgium
b Department of Hematology, Center for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Center, Ghent University Hospital, Ghent, Belgium
c Belgian National Reference Center for the Complement System, Laboratory of Immunology, LHUB-ULB, Université Libre de Bruxelles, Brussels, Belgium
d Laboratory of Immunoregulation, VIB Inflammation Research Center, Ghent, Belgium
e Department of Pediatrics, Division of Pediatric Pulmonology, Infectious Diseases and Immunology, Ghent University Hospital, Ghent, Belgium
f Division of Laboratory Medicine, Department of Clinical Chemistry, Ghent University Hospital, Ghent, Belgium
g Department of Pediatrics, Division of Pediatric Neurology, University Hospital Ghent, Ghent, Belgium
h Department of Pediatrics, Division of Pediatric Oncology and Immunology, Universitair Ziekenhuis Brussel, Jette, Belgium
i Department of Pediatrics, Department of Haematology-Oncology, Children's University Hospital Queen Fabiola, Université Libre de Bruxelles, Brussels, Belgium
j Department of Human Genetics, Institut de Pathologie et Génétique, Gosselies, Belgium
k Department of Pediatrics, Division of Pediatric Nephrology, University Hospital Ghent, Ghent, Belgium
l Department of Pediatrics, Division of Pediatric Nephrology, The Hospital for Sick Children, Toronto, Ontario, Canada
m Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, Université de Paris, Paris, France