Isabelle Meyts, MD, PhD a, ∗
These authors contributed equally to this study.
, Giorgia Bucciol, MD, PhD a, ∗
These authors contributed equally to this study.
, Isabella Quinti, MD b, Bénédicte Neven, MD, PhD c, d, e, Alain Fischer, MD, PhD c, d, e, f, g, Elena Seoane, MD, PhD h, Eduardo Lopez-Granados, MD, PhD i, Carla Gianelli, MD i, Angel Robles-Marhuenda, MD i, Pierre-Yves Jeandel, MD, PhD j, Catherine Paillard, MD, PhD k, Vijay G. Sankaran, MD, PhD l, m, Yesim Yilmaz Demirdag, MD n, Vassilios Lougaris, MD o, Alessandro Aiuti, MD, PhD p, q, Alessandro Plebani, MD, PhD o, Cinzia Milito, MD, PhD b, Virgil ASH. Dalm, MD, PhD r, Kissy Guevara-Hoyer, MD s, Silvia Sánchez-Ramón, MD s, Liliana Bezrodnik, MD t, Federica Barzaghi, MD p, Luis Ignacio Gonzalez-Granado, MD u, v, w, Grant R. Hayman, FRCP, FRCPath x, Gulbu Uzel, MD y, Leonardo Oliveira Mendonça, MD z, Carlo Agostini, MD, PhD aa, Giuseppe Spadaro, MD, PhD bb, Raffaele Badolato, MD, PhD cc, Annarosa Soresina, MD cc, François Vermeulen, MD, PhD dd, Cedric Bosteels, MD ee, ff, Bart N. Lambrecht, MD, PhD ee, ff, Michael Keller, MD gg, Peter J. Mustillo, MD hh, Roshini S. Abraham, PhD ii, Sudhir Gupta, MD, PhD n, Ahmet Ozen, MD jj, kk, ll, Elif Karakoc-Aydiner, MD jj, kk, ll, Safa Baris, MD jj, kk, ll, Alexandra F. Freeman, MD y, Marco Yamazaki-Nakashimada, MD mm, Selma Scheffler-Mendoza, MD mm, Sara Espinosa-Padilla, MD, PhD mm, Andrew R. Gennery, MD nn, oo, Stephen Jolles, MD, PhD pp, Yazmin Espinosa, MD qq, aaa, M. Cecilia Poli, MD qq, aaa, Claire Fieschi, MD, PhD c, rr, ss, Fabian Hauck, MD, PhD tt, Charlotte Cunningham-Rundles, MD, PhD uu, Nizar Mahlaoui, MD, PhD c, rr, theIUIS Committee of Inborn Errors of Immunity
Klaus Warnatz,
MD vv, ww, Kathleen E. Sullivan,
MD, PhD xx, Stuart G. Tangye,
PhD yy, zz, ⁎ ![](/templates/common/images/mail.png)
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a Department of Immunology and Microbiology, Inborn Errors of Immunity, Department of Pediatrics, University Hospitals Leuven and KU Leuven, Leuven, Belgium
b Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy
c Pediatric Hematology and Immunology Unit, Necker Hospital for Sick Children, Assistance Publique-Hopitaux de Paris, Paris, France
d Université de Paris, Paris, France
e Institut Imagine, Paris, France
f Institut National de la Santé et de la Recherche Médicale (INSERM) UMR 1163, Paris, France
g Collège de France, Paris, France
h Department of Pediatric Allergy and Immunology, and IISGM Gregorio Marañon University Hospital, Madrid, Spain
i University Hospital La Paz and Lymphocyte Pathophysiology in Immunodeficiencies Group, IdiPAZ Institute for Health Research, Rare Disease Network Research Center (CIBERER), Madrid, Spain
j Service de Médecine Interne, Centre Hospitalier Universitaire de Nice, Nice, France
k Pediatric Oncohematology and Bone Marrow Transplantation Unit, Hôpital de Hautepierre, CHRU, Strasbourg, France
l Division of Hematology/Oncology, Boston Children’s Hospital, Boston, Mass
m Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass
n Division of Basic and Clinical Immunology, Department of Medicine, University of California, Irvine, Calif
o Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, Department of Clinical and Experimental Sciences, University of Brescia an ASST- Spedali Civili of Brescia, Brescia, Italy
p San Raffaele Telethon Institute for Gene Therapy (TIGET), Pediatric Immunohematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute Milan, Milan, Italy
q Vita-Salute San Raffaele University, Milan, Italy
r Department of Internal Medicine, Division of Clinical Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands
s Department of Immunology, IML and IdSSC, Hospital Clínico San Carlos, University Complutense of Madrid, Madrid, Spain
t Center for Clinical Immunology, Immunology Group Children’s Hospital Ricardo Gutiérrez, Buenos Aires, Argentina
u Primary Immunodeficiencies Unit, Pediatrics, Hospital 12 Octubre, Madrid, Spain
v Research Institute Hospital 12 Octubre (i+12), Madrid, Spain
w Complutense University School of Medicine, Madrid, Spain
x Immunology Department, Epsom & St Helier University Hospitals NHS Trust, Carshalton, United Kingdom
y Laboratory of Clinical Immunology and Microbiology, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md
z Discipline of Clinical Immunology and Allergy, Department of Internal Medicine, University of São Paulo School of Medicine, São Paulo, Brazil
aa Department of Medicine, Division of First Internal Medicine and Center for Immunologic Rare Disease, Ca’ Foncello Treviso Hospital, University of Padua, Padua, Italy
bb Department of Translational Medical Sciences, Center for Basic and Clinical Immunology Research, University of Naples Federico II, Naples, Italy
cc Istituto Molecolare “A Nocivelli,” Department of Experimental and Clinical Sciences, University of Brescia & Asst Spedali civili, Brescia, Italy
dd Department of Pediatrics, University Hospitals Leuven, Leuven, Belgium
ee Laboratory of Immunoregulation and Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent, Belgium
ff Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium
gg Division of Allergy & Immunology, Children’s National Hospital, Washington, DC
hh Division of Allergic Diseases and Immunology, Nationwide Children’s Hospital, Columbus, Ohio
ii Department of Pathology and Laboratory Medicine, Nationwide Children’s Hospital, Columbus, Ohio
jj Division of Allergy and Immunology, Marmara University, Istanbul, Turkey
kk Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey
ll Istanbul Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Istanbul, Turkey
mm Immunodeficiencies Research Unit, National Institute of Pediatrics, Mexico City, Mexico
nn Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom
oo Paediatric Immunology and Haematopoietic Stem Cell Transplantation, Great North Children’s Hospital, Newcastle upon Tyne, United Kingdom
pp Immunodeficiency Centre for Wales, University Hospital of Wales, Cardiff, United Kingdom
qq Universidad del Desarrollo, Clínica Alemana de Santiago, Santiago de Chile, Chile
rr French National Reference Center for Primary Immune Deficiencies, Necker University, Paris, France
ss Department of Clinical Immunology, St-Louis Hospital-AP-HP, Paris, France
tt Department of Pediatrics, Dr von Hauner Children’s Hospital, University Hospital, Ludwig-Maximilians-Universität München, Munich, Germany
uu Departments of Medicine and Pediatrics, Mount Sinai School of Medicine, New York, NY
vv Center for Chronic Immunodeficiency, University of Freiburg, Freiburg, Germany
ww Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
xx Division of Allergy Immunology, Department of Pediatrics, The Children’s Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pa
yy Garvan Institute of Medical Research, Darlinghurst, Australia
zz St Vincent’s Clinical School, UNSW Sydney, Darlinghurst, Australia
aaa Hospital Roberto del Rio, Santiago, Chile