Maternal Autoimmune Disorders and Risk of Kawasaki Disease in Offspring - 27/01/21
Doi : 10.1016/j.jpeds.2020.02.016
Sabrina Belkaibech, MSc 1, 2, Brian J. Potter, MDCM, SM, FRCPC 3, 4, Harb Kang, MD, FRCPC 5, Ga Eun Lee, MScPH 2, 3, Marianne Bilodeau-Bertrand, MSc 2, Nathalie Auger, MD, MSc, FRCPC 2, 3, 6, ⁎ 
1 Department of Biology and Health, University of Lille, Lille, France
2 Bureau d’information et d’études en santé des populations, Institut national de santé publique du Québec, Montreal, Quebec, Canada
3 Health Innovation and Evaluation Hub, University of Montreal Hospital Research Centre, Montreal, Quebec, Canada
4 Division of Cardiology, Department of Medicine, University of Montreal Hospital Centre, Montreal, Quebec, Canada
5 Department of Rheumatology, Cité-de-la-Santé Hospital, Laval, Quebec, Canada
6 Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Quebec, Canada
∗Reprint requests: Dr Nathalie Auger, 190 Cremazie Blvd E, Montreal, Quebec, Canada H2P 1E2190 Cremazie Blvd EMontrealQuebecH2P 1E2Canada
Abstract |
We assessed the association between maternal autoimmune disorders and offspring risk of Kawasaki disease in a longitudinal cohort of 792 108 newborns. We found that maternal autoimmune disorders, especially autoimmune thyroiditis, may be risk factors for Kawasaki disease in children, particularly young children.
Le texte complet de cet article est disponible en PDF.Keywords : autoimmune disease, mucocutaneous lymph node syndrome, rheumatic diseases, thyroiditis, autoimmune, vasculitis
Plan
| Supported by the Heart and Stroke Foundation of Canada (G-18-0021776) and the Fonds de Recherche du Québec - Santé (34695). The study sponsors were not involved in study design; the collection, analysis, and interpretation of data; the writing of the report; and the decision to submit the manuscript for publication. The authors declare no conflicts of interest. |
© 2020
Elsevier Inc. Tous droits réservés.
Vol 222
P. 240 - juillet 2020 Retour au numéro
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