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An Integrated Infant and Young Child Feeding and Small-Quantity Lipid-based Nutrient Supplementation Program Is Associated with Improved Gross Motor and Communication Scores of Children 6-18 Months in the Democratic Republic of Congo - 27/01/21

Doi : 10.1016/j.jpeds.2020.01.023 
O. Yaw Addo, MS, PhD 1, 2, 3, , Katie Tripp, MSc 3, Simeon Nanama, PhD 4, Bope Albert, MSc 5, Fanny Sandalinas, MSc 6, Ambroise Nanema, MSc 4, Maria Elena Jefferds, PhD 3, Heather B. Clayton, PhD 3, Ralph D. Whitehead, PhD 3, Aashima Garg, PhD 7, Roland Kupka, ScD 7, Lindsey M. Locks, ScD, MPH 8, 7
1 Emory University Rollins School of Public, Hubert Department of Global Health & Global Health Institute, Atlanta, GA 
2 McKing Consulting Corporation, Atlanta, GA 
3 International Micronutrient Malnutrition Prevention and Control (IMMPaCT) Program, Nutrition Branch, Centers for Disease Control and Prevention, Atlanta, GA 
4 UNICEF-DRC, Kinshasa and Lubumbashi, Democratic Republic of Congo, DRC 
5 National Statistics Institute, Lubumbashi, DRC 
6 UNICEF-WCARO, Dakar, Senegal 
7 United Nations Children's Fund (UNICEF) Headquarters, New York, NY 
8 Harvard TH Chan School of Public Health, Boston, MA, USA 

Reprint requests: O. Yaw Addo, MS, PhD, Nutrition Branch, Centers for Disease Control and Prevention (CDC), 4770 Buford Hwy NE, Atlanta, GA 30341.Nutrition BranchCenters for Disease Control and Prevention(CDC)4770 Buford Hwy NEAtlantaGA30341

Abstract

Objective

To evaluate the impact of an infant, young child feeding practices–small-quantity lipid nutrient supplements (SQ-LNS) intervention on child development scores in children aged 6-18 months in the Katanga Province, Democratic Republic of Congo (DRC).

Study design

We analyzed data of 2595 children from 2 health zones in a quasi-experimental design with preimplementation and postimplementation surveys to evaluate program impact on child development scores. Standard care was received in the comparison health zone and the intervention health zone received standard care plus enhanced infant, young child feeding practices with a monthly supply of 28 SQ-LNS sachets for up to 1 year. Program exposure and communication and motor domains of the Ages and Stages questionnaire were collected to assess changes in child development scores. A quasi-intent-to-treat and adjusted difference-in-difference analyses were used to quantify impact of the enhanced compared with the standard package.

Results

In adjusted models contrasting endline with baseline, there was a greater relative increase in proportion of children with normal communication (difference-in-difference, +13.7% [95%CI, 7.9-19.6; P < .001] and gross motor scores, +7.4% [95% CI: 1.3-13.5; P < .001]) in the intervention vs comparison health zones. Further, in separate analyses among children of intervention health zone at endline, each additional SQ-LNS distribution was associated with +0.09 (95% CI, 0.03-0.16) z-score unit increase in gross motor scores (P < .01).

Conclusions

The integrated infant, young child feeding practice-SQ-LNS intervention was positively associated with larger relative improvements in measures of child communication and motor development in the Katanga province of DRC.

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Keywords : IYCF, SQ-LNS, child development, ages and Stages scores

Abbreviations : ASQ, CHW, DiD, DRC, GLMM, IYCF, RCT, SQ-LNS


Plan


 O.Y.A. is a McKing Consulting Corporation Contractor assigned to the CDC-Nutrition Branch, Atlanta. K.T. was employed by the CDC, Atlanta when this work was performed.
 The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the US Centers for Disease Control and Prevention, the United Nations Children's Fund (UNICEF) or the Democratic Republic of Congo's Ministry of Health Department of Nutrition (PRONANUT). Nutriset contributed to the formative work and packaging design for the small-quantity lipid-nutrient supplements (SQ-LNS), a component of this integrated program. They had no role in the survey design, data collection, statistical analyses, data interpretation or writing of this manuscript. The authors declare no conflicts of interest.


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Vol 222

P. 154-163 - juillet 2020 Retour au numéro
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