Impact of use stent with a polyethylene terephthalate micro-net covering on coronary microvascular dysfunction in patients with acute myocardial infarction - 09/01/21
Résumé |
Aims |
We aimed to investigate whether micro-net on stent could preserve the index of msicrocirculatory resistance (IMR) after primary percutaneous coronary intervention (PCI) in patients with acutemyocardial infarction (AMI).
Methods and results |
Fifty deux patients with AMI were randomized into two groups: primary PCI with micro-net on stent (MGUARD group, n=25) and primary PCI with any commercially available (DES group, n=27). As the primary endpoint, IMR was measured immediately after primary PCI using a pressure-temperature sensor-tipped coronary wire. The secondary endpoint was the left ventricular ejection fraction (LVEF) at six-month follow-up. The IMR in MGUARD group was significantly lower than in DES group (39.6±26.2 U vs. 75.4±60.5 U, P=0.01). No significant differences in baseline EF (56.2±10.3% vs. 54.9±7.73%, P=0.7), however, there were significant differences in follow-up EF (63.2±3.8% vs. 54.7±7.79%, P=0.001).
Conclusion |
A micro-net on stent significantly improved CMVD compared with a traditional DES in primary PCI and appear as a useful technological option to manage the thrombus.
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Vol 13 - N° 1
P. 11 - janvier 2021 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.