Impact of Covid-19 infection in high-risk coronary patients - 09/01/21
, B. Marchandot 1, K. Matsushita 1, 2, A. Curtiaud 1, A. Elidrissi 1, A. Trimaille 1, M. Kibler 1, T. Cardi 1, J.O.E. Heger 1, S. Hess 1, A. Reydel 1, S. Fafi-Kremer 3, V. Schini-Kerth 2, L. Jesel 1, 2, P. Ohlmann 1, O. Morel 1, 2
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Résumé |
Background |
Coronary artery disease (CAD) has been recognized as a major determinant of Covid-19 vulnerability and severity. We sought to compare demographic characteristics, clinical presentation, and outcomes for Covid-19 in a large cohort of chronic CAD patients living in Strasbourg's cluster region (Fig. 1).
Methods |
Follow-up was conducted by telephone interviews performed by cardiologists one month after the start of the French lockdown. The primary outcome was the composite of death or hospitalization related to Covid-19 infection. Secondary endpoints included Covid-19 related death, Covid-19 related hospitalization, intensive care unit (ICU) admission, allcause mortality, cardiovascular (CV) mortality and healthcare compliance.
Results |
Out of 891 patients included, twenty CAD patients (2.2%) had RT-PCR confirmed Covid-19 infection. Confirmed or suspect cases were evidenced in 48 patients (5.4%). Covid-19 patients showed lower left ventricular ejection fraction, were more frequently obese, less likely to smoke or follow lipid lowering therapy. The composite of death or hospitalization related to Covid-19 was 90%. Mortality rate was 30% among confirmed Covid-19 patients. Drugs’ discontinuation rate was low (1.1%) during the confinement. Reticence to consult a healthcare professional occurred in 6.4%. Postponement or cancellation of non-essential medical visits occurred in 15,7% (Table 1).
Conclusions |
Coronary patients from a large French cluster of COVID-19 showed a high risk of Covid-19 infection and worse in-hospital outcomes.
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Vol 13 - N° 1
P. 11-12 - janvier 2021 Retour au numéro
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