Diagnostic value of modified systemic inflammation score for prediction of malignancy in patients with indeterminate thyroid nodules - 08/12/20
, Birol Korukluoğlu a, Buket Altun Özdemir a, Neşe Yakşi b, Barış Saylam a, Mesut Tez cAbstract |
Background |
Approximately 20% of the thyroid biopsies render an indeterminate (ID) cytology. We evaluated the diagnostic value of preoperative modified systemic inflammation score (mSIS) in predicting the malignancy of ID thyroid nodules (TNs).
Methods |
Data of 162 patients with indeterminate TNs were examined retrospectively. The mSIS was calculated as follows: mSIS 0 [patients with albumin (ALB) ≥ 4.0 g/dL and lymphocyte-to-monocyte ratio (LMR) ≥ 3.4], mSIS 1 [ALB < 4.0 g/dL or LMR < 3.4], and mSIS 2 [ALB < 4.0 g/dL and LMR < 3.4].
Results |
Patients were classified into mSIS 0 (n = 105), mSIS 1 (n = 34) and mSIS 2 (n = 23) groups. The malignancy rates for the mSIS 0, 1 and 2 groups were 34.3%, 64.7% and 100% respectively. Preoperative mSIS was significantly associated with the presence of thyroid malignancy (p < 0.001).
Conclusions |
If the mSIS of patients with ID cytology is 1 or 2, appropriate surgical treatment should be performed without delay, due to the increased risk of malignancy.
Le texte complet de cet article est disponible en PDF.Highlights |
• | Modified systemic inflammation score (mSIS) is an easy and cost-effective method to assess the risk of malignancy. |
• | mSIS may provide important contributions to clinicians in predicting malignancy risk of indeterminate TNs. |
• | This is the first report that establishes a positive association between preoperative mSIS and thyroid malignancies. |
Keywords : Albumin, Thyroid cancer, Lymphocyte-to-monocyte ratio, Systemic inflammation score, Thyroid nodules
Plan
Vol 221 - N° 1
P. 117-121 - janvier 2021 Retour au numéro
Article précédent
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