Implementation of a systematic comprehensive geriatric assessment for elderly patients suspected of pulmonary hypertension - 29/11/20
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Highlights |
• | Pulmonary hypertension (PH) is incrementally suspected in elderly patients. |
• | With advanced age, low prevalence of PAH as increased prevalence of chronic thromboembolic PH makes the management of PH suspicion in the elderly more complex. |
• | Implementation of a comprehensive geriatric assessment in elderly patients referred to a PH suspicion is possible and leads to stop PH diagnostic work-up in a third of cases. |
• | Among patients with pulmonary hypertension, pre-capillary pulmonary hypertension was the most common group, with a high proportion of chronic thromboembolic PH. |
Abstract |
Background |
The phenotype of patients seen for a suspicion of pulmonary hypertension has changed, with an increasing age and frequency of comorbidities. Selection of elderly patients, in whom a classical work-up is mandatory, is challenging. Comprehensive geriatric assessment (CGA) has modified the management of elderly patients with cancer. Pulmonary hypertension (PH) shares with cancer a functional impact and may evolve rapidly, depending on the group of PH. We assessed the impact of a systematic CGA in patients over 70 years old referred for a suspicion of PH.
Methods |
A standardised CGA was performed on every patient older than 70 years old, referred for a PH suspicion, before considering invasive tests for diagnosis and treatment, between July 2014 and May 2019. Our primary aim was to describe the impact of CGA on the decision to stop or pursue the recommended diagnostic work-up for PH.
Results |
Among the thirty-one patients evaluated [mean age 81,5 (72–91) years], a negative CGA leads to stop the diagnostic work-up in eleven patients. Among the nineteen remaining patients, sixteen had confirmed PH, with half being chronic thromboembolic pulmonary hypertension.
Conclusions |
Our study indicates that comprehensive geriatric assessment could be an excellent first screen for elderly patients referred for a PH suspicion. Involving a geriatric physician stopped the investigations in one third of patients. In patients with a favourable CGA, PH was confirmed in most of the cases, with chronic thromboembolic pulmonary hypertension being the first cause of PH.
Le texte complet de cet article est disponible en PDF.Keywords : Geriatric assessment, Pulmonary hypertension, Elderly
Abbreviations : ADL, BMI, CGA, CTEPH, ECOG, GDS, IADL, LVEF, MMS, MNA, NYHA, PAH, PH, sPAP, TTE, V/Q lung scan
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