Gut microecology: Why our microbes could be key to our health - 28/10/20
, Xiao Zhu a, b, c, f, ⁎ Bienvenue sur EM-consulte, la référence des professionnels de santé.
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Highlights |
• | The structure and function of gut microbiota can affect the health of the human body in many ways. |
• | Diseases that happened in the body's major systems are associated with the changes in gut microbiota. |
• | Gut microbiota can promote the occurrence and development of tumors through direct contact with the tumor cells. |
• | Gut microbiomes can regulate the immune system and linking to body metabolism. |
Abstract |
The human body contains a large number of microorganisms, and the gut microecology environment contains the largest number and types of microorganisms. The structure and function of gut microbiota are closely related to the health of the human body. In a cascade of studies, the diversity of gut microbiota and its metabolite often found changed in patients or mice model. What kind of gut microbiota that associated with the occurrence or treatment of diseases were also found in many studies. Gut microbiota and its products can affect the function of the human body. Short-chain fatty acids, bile acid, indoles and so on were found can regulate the inflammation, immune response to affect the process of diseases. Immune cells like natural killer T cells, CD3 + T cells were also found had a link to gut microbiota which associated with diseases. Changes in gut microbiota are associated with changes in the body's major systems, such as the digestive system, the endocrine system, the cardiovascular system, the endocrine and metabolic system, the urinary system diseases, the respiratory system and so on. It is of great significance to study gut microecology for the prevention and treatment of various human diseases.
Le texte complet de cet article est disponible en PDF.Abbreviations : IBD, CD, UC, ICI, NKT, IFN-γ, CXCL16, FAP, IL-17, CARD9, TET2, PMP, IL-6, TLR4, SCFA, QoL, SCZ, GPR43, CHD, AhR, IGN, FOS, G6pc, MetS, OTUs, GNS, FLNA, SLE, Th17, CX3CR1, MS
Keywords : Gut microecology, Gut microbiomes, Digestive system, Metabolisms, Treatment
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Vol 131
Article 110784- novembre 2020 Retour au numéro
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