Exhausted phenotype of follicular CD8 T cells in CVID - 05/10/20
Doi : 10.1016/j.jaci.2020.02.025
Adam Klocperk, MD, PhD a, b, c 
, Susanne Unger, PhD a, b, d, David Friedmann, MSc a, b, e, Maximilian Seidl, MD f, Katharina Zoldan, PhD g, Jens Pfeiffer, MD h, Oliver Hausmann, MD i, Vladimir Benes, MD, PhD j, Geoffroy Andrieux, PhD k, l, m, Tobias Boettler, MD, PhD g, Anna Sediva, MD c, Bertram Bengsch, MD, PhD g, n, Klaus Warnatz, MD a, b
, Susanne Unger, PhD a, b, d, David Friedmann, MSc a, b, e, Maximilian Seidl, MD f, Katharina Zoldan, PhD g, Jens Pfeiffer, MD h, Oliver Hausmann, MD i, Vladimir Benes, MD, PhD j, Geoffroy Andrieux, PhD k, l, m, Tobias Boettler, MD, PhD g, Anna Sediva, MD c, Bertram Bengsch, MD, PhD g, n, Klaus Warnatz, MD a, b a Divison of Immunodeficiency, Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
b Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
c Department of Immunology, 2nd Faculty of Medicine, Charles University in Prague and University Hospital in Motol, Prague, Czech Republic
d Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland
e Faculty of Biology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
f Institute for Surgical Pathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
g Department of Medicine II, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
h Department of Otorhinolaryngology–Head and Neck Surgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
i Löwenpraxis and Klinik St Anna, Luzern, Switzerland
j Genomics Core Facility, EMBL Heidelberg, Heidelberg, Germany
k Institute of Medical Bioinformatics and Systems Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
l German Cancer Consortium (DKTK), partner site Freiburg, Heidelberg, Germany
m German Cancer Research Center (DKFZ), Heidelberg, Germany
n Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany
| This study was funded by a grant issued by the Deutsche Forschungsgemeinschaft (grant no. SFB 1160 IMPATH; project A04 to K.W. and project A03 to B.B.), a personal grant of the European Society for Immunodeficiencies to A.K., and a grant issued by the Czech health research council and Ministry of Health, Czech Republic (grant no. AZV NV18-05-00162). |
|
| Disclosure of potential conflict of interest: The authors declare that they have no relevant conflicts of interest. |
© 2020
American Academy of Allergy, Asthma & Immunology. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 146 - N° 4
P. 912 - octobre 2020 Retour au numéro
Article précédent
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