Characteristics, Cardiac Involvement, and Outcomes of Multisystem Inflammatory Syndrome of Childhood Associated with severe acute respiratory syndrome coronavirus 2 Infection - 19/08/20

Doi : 10.1016/j.jpeds.2020.06.044

Christine A. Capone, MD, MPH ^1,², Anupama Subramony, MD, MBA ^1,², Todd Sweberg, MD, MBA ^1,², James Schneider, MD ^1,², Sareen Shah, MD ^1,², Lorry Rubin, MD ^1,², Charles Schleien, MD, MBA ^1,^2,^⁎ ,
the Northwell Health COVID-19 Research Consortium
Shilpi Epstein, MD ^1,², Jennifer C. Johnson, MS, MA ³, Aaron Kessel, MD, MS ^1,², Nila Misra, MD ^1,², Elizabeth Mitchell, MD ^1,², Nancy Palumbo, MD ^1,², Sujatha Rajan, MD ^1,², Josh Rocker, MD ^1,², Kristy Williamson, MD ^1,², Karina W. Davidson, PhD, MASc ^1,³
¹ Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY
² Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY
³ Institute of Health Innovations and Outcomes Research, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY

^∗Reprint requests: Charles Schleien, MD, MBA, Philip Lanzkowsky Professor and Chair of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, 269-01 76th Ave, New Hyde Park, NY 11040Philip Lanzkowsky Professor and Chair of PediatricsDonald and Barbara Zucker School of Medicine at Hofstra/Northwell269-01 76th AveNew Hyde ParkNY11040

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Abstract

We report on the presentation and course of 33 children with multisystem inflammatory syndrome in children and confirmed severe acute respiratory syndrome coronavirus 2 infection. Hemodynamic instability and cardiac dysfunction were prominent findings, with most patients exhibiting rapid resolution following anti-inflammatory therapy.

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Keywords : kawasaki disease, adolescents, coronary aneurysm, inflammation

Abbreviations : CDC, COVID-19, IVIG, LV, LVEF, MIS-C, SARS-CoV-2

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Vol 224

P. 141-145 - septembre 2020 Retour au numéro

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Characteristics, Cardiac Involvement, and Outcomes of Multisystem Inflammatory Syndrome of Childhood Associated with severe acute respiratory syndrome coronavirus 2 Infection - 19/08/20

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