04-33 - ECHOCARDIOGRAPHIC ASSESSMENTS OF LEFT ATRIAL FUNCTION AND FILLING PRESSURE CORRELATE WITH EXERCISE CAPACITY IN PATIENTS WITH CHRONIC CONGESTIVE HEART FAILURE - 09/04/08
DONAL,
Renaud GERVAIS,
Christian de PLACE,
Arnaud ROSIER,
François CARRE,
Philippe MABO
Voir les affiliationsAims: Doppler echocardiography is well recognized as the primary non-invasive imaging technique to assess global and regional cardiac function. Cardiopulmonary exercise testing (CPET) has become a powerful tool to predict outcome in chronic heart failure (CHF). We studied the relationship between resting echocardiographic parameters and exercise tolerance in CHF patients.
Methods and results: Transthoracic echocardiography and standardized CPET were performed in 75 patients (59€11 years) with CHF, New York Heart Association functional class II-III. Systolic and diastolic function, filling pressures, left ventricular (LV), right ventricular (RV), and left atrial (LA) regional function were assessed using Doppler tissue velocities and strain values (fig1). Maximal workload (86€41watts) and peak O2 (14.6€3.1ml/min/kg) correlated with LV filling pressure estimates (E/Ea and E/Vp) but also with end-diastolic pulsed Doppler tissue velocity at the mitral annulus (Aa), LA volume and regional LA function assessed by strain analysis. In multivariate analysis, maximum workload and peak O2 were shown to correlate with RV peak strain, although Aa and E/Ea were the best predictors of exercise capacity.
Conclusion: Echocardiography provides useful information to assess LV, RV but also LA function. Evaluation of LA function should not be omitted. In addition to E/Ea, peak Aa velocity should be assessed in CHF evaluation.
Plan
© 2007 Elsevier Masson SAS. Tous droits réservés.
Vol 100 - N° 12
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