Severe Coronavirus Disease-2019 in Children and Young Adults in the Washington, DC, Metropolitan Region - 22/07/20

Doi : 10.1016/j.jpeds.2020.05.007

Roberta L. DeBiasi, MD, MS ^1,^2,^3,^⁎ , Xiaoyan Song, MBBS, PhD ^2,⁴, Meghan Delaney, MD ^2,⁵, Michael Bell, MD ^2,⁶, Karen Smith, MD ^2,⁷, Jay Pershad, MD ^2,⁸, Emily Ansusinha, MA ¹, Andrea Hahn, MD, MS ^1,², Rana Hamdy, MD, MPH ^1,², Nada Harik, MD ^1,², Benjamin Hanisch, MD ^1,², Barbara Jantausch, MD ^1,², Adeline Koay, MBBS ^1,², Robin Steinhorn, MD ^2,⁹, Kurt Newman, MD ^2,¹⁰, David Wessel, MD ^2,⁶
¹ Division of Pediatric Infectious Diseases, Children's National Hospital, Washington, DC
² Department of Pediatrics, The George Washington University School of Medicine and Health Sciences, Washington, DC
³ Department of Microbiology, Immunology and Tropical Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC
⁴ Division of Infection Control and Epidemiology, Children's National Hospital, Washington, DC
⁵ Division of Laboratory Medicine and Pathology, Children's National Hospital, Washington, DC
⁶ Division of Critical Care Medicine, Children's National Hospital, Washington, DC
⁷ Division of Hospitalist Medicine, Children's National Hospital, Washington, DC
⁸ Division of Emergency Medicine, Children's National Hospital, Washington, DC
⁹ Division of Neonatology, Children's National Hospital, Washington, DC
¹⁰ Chief Executive Officer, Division of Pediatric Surgery, Children's National Hospital, Washington, DC

^∗Reprint requests: Roberta L. DeBiasi, MD, MS, Chief, Division of Pediatric Infectious Diseases, Professor of Pediatrics, Microbiology, Immunology and Tropical Medicine, Children's National Hospital, 111 Michigan Ave NW, West Wing 3.5 Suite 100, Washington, DC 20010.Division of Pediatric Infectious DiseasesProfessor of Pediatrics, Microbiology, Immunology and Tropical MedicineChildren's National Hospital111 Michigan Ave NWWest Wing 3.5 Suite 100WashingtonDC20010

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Abstract

Despite worldwide spread of severe acute respiratory syndrome coronavirus-2, few publications have reported the potential for severe disease in the pediatric population. We report 177 infected children and young adults, including 44 hospitalized and 9 critically ill patients, with a comparison of patient characteristics between infected hospitalized and nonhospitalized cohorts, as well as critically ill and noncritically ill cohorts. Children <1 year and adolescents and young adults >15 years of age were over-represented among hospitalized patients (P = .07). Adolescents and young adults were over-represented among the critically ill cohort (P = .02).

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Keywords : SARS-CoV-2, COVID-19, pediatric, hospitalization, critical care

Abbreviations : COVID-19, MIS-C, SARS-CoV-2

Plan

Underlying Medical Conditions

Symptoms

Critically Ill Cohort

Co-infection

Discussion

R.S. serves as an Associate Editor for The Journal of Pediatrics. The other authors declare no conflicts of interest.

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Vol 223

P. 199 - août 2020 Retour au numéro

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Severe Coronavirus Disease-2019 in Children and Young Adults in the Washington, DC, Metropolitan Region - 22/07/20

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