Advances in the relationship between coronavirus infection and cardiovascular diseases - 30/05/20

Doi : 10.1016/j.biopha.2020.110230

Mengmeng Zhao ^a,^b,^c,^{^{1
These authors contributed equally.}}, Menglong Wang ^a,^b,^c,^{^{1
These authors contributed equally.}}, Jishou Zhang ^a,^b,^c,^{^{1
These authors contributed equally.}}, Jing Ye ^a,^b,^c, Yao Xu ^a,^b,^c, Zhen Wang ^a,^b,^c, Di Ye ^a,^b,^c, Jianfang Liu ^a,^b,^c, Jun Wan ^a,^b,^c,⁎
^a Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China
^b Cardiovascular Research Institute, Wuhan University, Wuhan, China
^c Hubei Key Laboratory of Cardiology, Wuhan, China

^⁎Corresponding author at: Department of Cardiology, Renmin Hospital of Wuhan University, 238, Jiefang Road, Wuhan, 430060, China.Department of CardiologyRenmin Hospital of Wuhan University238, Jiefang RoadWuhan430060China

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Highlights

•	Underlying cardiovascular diseases increase the incidence and severity of coronavirus infection.
•	Cardiac injury is common in patients with COVID-19. It is a risk factor for mortality of COVID-19 patients.
•	Cardiovascular complications are mainly related to fever, inflammation, the direct effects of Covs and drug side effects.

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Abstract

The outbreak of coronavirus disease 2019 (COVID-19) has once again aroused people's concern about coronavirus. Seven human coronaviruses (HCoVs) have been discovered so far, including HCoV-229E, HCoV-NL63, HCoV-OC43, HCoV-HKU115, severe acute respiratory syndrome coronavirus, Middle East respiratory syndrome coronavirus and severe acute respiratory syndrome coronavirus 2. Existing studies show that the cardiovascular disease increased the incidence and severity of coronavirus infection. At the same time, myocardial injury caused by coronavirus infection is one of the main factors contributing to poor prognosis. In this review, the recent clinical findings about the relationship between coronaviruses and cardiovascular diseases and the underlying pathophysiological mechanisms are discussed. This review aimed to provide assistance for the prevention and treatment of COVID-19.

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Keywords : Coronavirus, Coronavirus disease 2019, Cardiovascular disease, Severe acute respiratory syndrome coronavirus, Middle East respiratory syndrome coronavirus

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Vol 127

Article 110230- juillet 2020 Retour au numéro

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