Measuring atopic eczema symptoms in clinical practice: The first consensus statement from the Harmonising Outcome Measures for Eczema in clinical practice initiative - 14/04/20

Doi : 10.1016/j.jaad.2019.12.055

Yael A. Leshem, MD, MCR ^a,^b,^⁎ , Joanne R. Chalmers, PhD ^c, Christian Apfelbacher, PhD ^d,^e, Masutaka Furue, MD, PhD ^f, Louise A.A. Gerbens, MD, PhD ^g, Cecilia A.C. Prinsen, PhD ^h, Jochen Schmitt, MD, MPH ⁱ, Phyllis I. Spuls, MD, PhD ^g, Kim S. Thomas, PhD ^c, Hywel C. Williams, DSc ^c, Eric L. Simpson, MD, MCR ^j
on behalf of the
Harmonising Outcome Measures for Eczema (HOME) initiative
^a Divison of Dermatology, Rabin Medical Center, Petach-Tikva, Israel
^b Sackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel
^c Centre of Evidence-Based Dermatology, University of Nottingham, Nottingham, United Kingdom
^d Medical Sociology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany
^e Institute of Social Medicine and Health Systems Research, Otto von Guericke University Magdeburg, Magdeburg, Germany
^f Department of Dermatology, Kyushu University, Fukuoka, Japan
^g Department of Dermatology, Amsterdam UMC, location Academic Medical Center, University of Amsterdam, Amsterdam Public Health, Infection and Immunity, Amsterdam, the Netherlands
^h Amsterdam UMC, VU University, Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands
ⁱ Center for Evidence-based Healthcare, Medical Faculty Carl Gustav Carus, Dresden, Germany
^j Department of Dermatology, Oregon Health & Science University, Portland, Oregon

^∗Correspondence to: Yael A. Leshem, MD, MCR, Department of Dermatology, Rabin Medical Center, 39 Zabotinsky St, Petach-Tikva 4941492, Israel.Department of DermatologyRabin Medical Center39 Zabotinsky StPetach-Tikva4941492Israel

Abstract

Background

Measuring patient-centered outcomes in clinical practice is valuable for monitoring patients and advancing real-world research. A new initiative from the Harmonising Outcome Measures for Eczema (HOME) group aims to recommend what might be recorded for atopic eczema patients in routine clinical care.

Objectives

Prioritize outcome domains to measure atopic eczema in clinical practice and select valid and practical outcome measurement instruments for the highest-priority domain.

Methods

An online survey of HOME members identified and ranked 21 possible health domains. Suitable instruments were then selected for the top-prioritized domain at the HOME VI meeting, using established consensus processes informed by systematic reviews of instrument quality.

Results

Patient-reported symptoms was the top-prioritized domain. In accordance with psychometric properties and feasibility, there was consensus that the recommended instruments to measure atopic eczema symptoms in clinical practice are the POEM, the PO-SCORAD index, or both. The numeric rating scale for itch received support pending definition and validation in atopic eczema.

Conclusion

Following the first step of the HOME Clinical Practice initiative, we endorse using the POEM, the PO-SCORAD index, or both for measuring atopic eczema symptoms in clinical practice. Additional high-priority domains for clinical practice will be assessed at subsequent HOME meetings.

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Key words : outcomes, outcome measures, instruments, atopic dermatitis, atopic eczema, eczema, Harmonising Outcome Measures for Eczema, HOME, clinical practice

Abbreviations used : HOME, POEM, PO-SCORAD

Plan

Introduction

Methods and results

Step 1: define scope

Step 2: develop a prioritized set of outcome domains

Step 3, stages 1 to 2: identify instruments used to measure symptoms in atopic eczema and establish their extent and quality

Step 3, stages 3 to 5: selection of recommended instruments

Recommendation

	Funding sources: None.
	Conflicts of interest: None disclosed.
	Reprints not available from the authors.

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Vol 82 - N° 5

P. 1181-1186 - mai 2020 Retour au numéro

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Measuring atopic eczema symptoms in clinical practice: The first consensus statement from the Harmonising Outcome Measures for Eczema in clinical practice initiative - 14/04/20

Abstract

Background

Objectives

Methods

Results

Conclusion

Plan

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