The Brain-Heart Connection in Sympathetically Triggered Inherited Arrhythmia Syndromes - 13/03/20
Abstract |
Sympathetically triggered inherited arrhythmia syndromes, including the long QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardia (CPVT), can cause sudden cardiac death in young individuals with structurally normal hearts. With cardiac events typically triggered by physical or emotional stress, not surprisingly, two of the most common treatments are neuromodulators, including mainstay beta blocker pharmacotherapy, and surgical sympathetic cardiac denervation. This review updates the clinician on the relevant anatomy and physiology of the cardiac autonomic nervous system, outlines neurocardiac arrhythmia mechanisms, and discusses the latest rationale for a neurocardiac therapeutic approach to manage sympathetic-induced arrhythmia in patients with inherited cardiac disease.
Le texte complet de cet article est disponible en PDF.Keywords : Long QT syndrome, Catecholaminergic polymorphic ventricular tachycardia, Neurocardiac, Sympathetic nervous system, Beta blockers, Cardiac sympathetic denervation
Plan
Vol 29 - N° 4
P. 529-537 - avril 2020 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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