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Age, knowledge, preferences, and risk tolerance for invasive cardiac care - 18/12/19

Doi : 10.1016/j.ahj.2019.09.008 
Michael G. Nanna, MD , Eric D. Peterson, MD, MPH, Angie Wu, MS, Tina Harding, BSN, Anthony N. Galanos, MD, Lisa Wruck, PhD, Karen P. Alexander, MD
 Duke Clinical Research Institute, Durham, NC 

Reprint requests: Michael G. Nanna, MD, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27710.Duke Clinical Research Institute, Duke University School of MedicineDurhamNC27710

Abstract

Background/objectives

The extent to which individual knowledge, preferences, and priorities explain lower use of invasive cardiac care among older vs. younger adults presenting with acute coronary syndrome (ACS) is unknown. We directly surveyed a group of patients to ascertain their preferences and priorities for invasive cardiovascular care.

Design

We performed a prospective cohort study of adults hospitalized with ACS. We surveyed participants regarding their knowledge, preferences, goals, and concerns for cardiac care, as well as their risk tolerance for coronary artery bypass grafting (CABG).

Setting

Single academic medical center.

Participants

Six hundred twenty-eight participants (373 <75 years old; 255 ≥75 years old).

Measurements

We compared baseline characteristics, knowledge, priorities, and risk tolerance for care across age strata. We also assessed pairwise differences with 95% confidence intervals (CI) between age groups for key variables of interest.

Results

Compared with younger patients, older participants had less knowledge of invasive care; were less willing to consider cardiac catheterization (difference between 75–84 and< 65 years old: −7.8%, 95% CI: −14.4%,-1.3%; for ≥85 vs. <65: −15.7%, 95% CI: −29.8%,-1.6%), percutaneous coronary intervention (difference between 75–84 and< 65 years old: −12.8%, 95% CI: −20.8%,-4.8%; for ≥85 vs. <65: −24.8%, 95% CI: −41.2%,-8.5%), and CABG (difference between 75–84 and< 65 years old: −19.0%, 95% CI: −28.2%,-9.9%; for ≥85 vs. <65: −39.1%, 95% CI: −56.0%,-22.2%); and were more risk averse for CABG surgery (p < .001), albeit with substantial inter-individual variability and individual outliers. Many patients who stated they were not initially willing to undergo an invasive cardiovascular procedure actually ended up undergoing the procedure (49% for cardiac catheterization and 22% for PCI or CABG).

Conclusion

Age influences treatment goals and willingness to consider invasive cardiac care, as well as risk tolerance for CABG. Individuals' willingness to undergo invasive cardiovascular procedures loosely corresponds with whether that procedure is performed after discussion with the care team.

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Plan


 Impact statement: Our study is unique in describing the role of patient age in the knowledge, preferences, and priorities for invasive cardiovascular care at the time of hospitalization for acute coronary syndrome. Older participants prioritized physical and mental functioning and quality of life more often than younger participants who focused mostly on survival. Older adults were more risk averse than younger peers when considering CABG surgery, with median risk tolerance of just 1% among individuals ≥85 years old, yet preferences vary widely within each age group. In addition, a number of patients who were not initially willing to consider invasive procedures ended up undergoing those procedures. While patient age was strongly associated with trends in decision-making preferences and priorities, variation persists at every age making it vital to solicit individual priorities.


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Vol 219

P. 99-108 - janvier 2020 Retour au numéro
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