High prevalence of cholesterol-rich atherosclerotic lesions in ancient mummies: A near-infrared spectroscopy study - 07/11/19
Doi : 10.1016/j.ahj.2019.06.018
Mohammad Madjid, MD, MS a, ⁎ 
a Department of Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX
∗Reprint requests: Mohammad Madjid, MD, Department of Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, 6431 Fannin, MSB 1.246, Houston, TX 77030Department of Medicine, McGovern Medical SchoolUniversity of Texas Health Science Center at Houston6431 Fannin, MSB 1.246HoustonTX77030
Payam Safavi-Naeini, MD b
b Electrophysiology Clinical Research & Innovations, Texas Heart Institute, Houston, TX
Robert Lodder, PhD c
c Department of Pharmaceutical Sciences, University of Kentucky, Lexington, KY, United States
Abstract |
Computed tomography has been used previously in mummies to detect arterial calcification, which is a marker of later-stage atherosclerosis. Here, using the novel approach of near-infrared spectroscopy, we detected cholesterol-rich atherosclerotic plaques in arterial samples from ancient mummies. In this proof-of-concept study, we are the first to noninvasively detect these earlier-stage lesions in mummies from different geographical areas, suggesting that atherosclerosis has been present in humans since ancient times.
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| ☆ | Declaration of conflict interest: none. |
| ☆☆ | The authors are solely responsible for the design and conduct of this study, all study analyses, the drafting and editing of the paper, and its final contents. |
© 2019
Elsevier Inc. Tous droits réservés.
Vol 216
P. 113-116 - octobre 2019 Retour au numéro
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