Number of botulinum toxin injections needed to stop requests for treatment for chronic lateral epicondylar tendinopathy. A 1-year follow-up study - 20/09/19
, Alexandre Creuzé a, Hervé Petit a, Claire Delleci a, Patrick Dehail a, b, Mathieu de Seze a, b
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Highlights |
• | At 1-year follow-up of the effect of botulinum toxin injections on chronic epicondylar tendinopathy, 1 or 2 botulinum toxin injections seemed enough to obtain pain relief. |
• | Quality of life, pain and maximal gripping force improved after botulinum toxin injections during follow-up. |
• | Repercussion of pain on daily and professional activities decreased after botulinum toxin injections during follow-up. |
Abstract |
Background |
Epicondylar tendinopathy (“tennis elbow”) is a serious issue in manual labourers. Symptoms can persist over months or even more than 1 year, even when treated with trinitrine patches, acupuncture, sclerosis of neovessels, shock-wave therapy, autologous blood injections, platelet-rich plasma or hyaluronic acid. Botulinum toxin (BoNT-A) injections showed promising short-term results, but the long-term beneficial effects are not yet known.
Objective |
We aimed to assess the long-term effect, side effects and recurrence rate after BoNT-A injections on chronic lateral epicondylar tendinopathy during 1 year.
Methods |
This open study followed a 3-month randomized controlled trial. We included 50 patients followed at day 0 (V0), 90 (V1), 180–270 (V2) and 365 (V3). The main judgment criterion was the number of BoNT-A injections required to achieve pain relief with no further request for treatment by the patient.
Results |
After one BoNT-A injection, 22/50 (44%) patients did not ask for further treatment during follow-up because of complete pain relief, and 20/50 (40%) asked for a second BoNT-A injection. For 20 patients with a second injection, 18 (90%) did not ask for further treatment during follow-up. Only 1 patient had a recurrence of pain after an initial pain relief of greater than 75%. Quality of life, and painful and maximal gripping force improved significantly at V1, V2 and V3 as compared with V0, and repercussions on daily and professional activities decreased significantly (P<0.05).
Conclusions |
One or 2 BoNT-A injections has favourable results for chronic epicondylar tendinopathy.
Le texte complet de cet article est disponible en PDF.Keywords : Tennis elbow, Epicondylar tendinopathy, Botulinum toxin A, Pain, Quality of life, Gripping force
Plan
Vol 62 - N° 5
P. 336-341 - septembre 2019 Retour au numéro
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