New Cluster of Acute Flaccid Myelitis in Western Pennsylvania - 19/09/19

Doi : 10.1016/j.annemergmed.2019.01.024

Natan Cramer, MD ^a, Neil Munjal, MD ^e, Danielle Ware, DO ^f, Sriram Ramgopal, MD ^a, Dennis Simon, MD ^e, Megan C. Freeman, MD, PhD ^b, Marian G. Michaels, MD, MPH ^b, Christopher Stem, MD ^a, Kavita Thakkar, MD ^c, John V. Williams, MD ^b, Ashok Panigrahy, MD ^d, Desiree N.W. Neville, MD ^a, Sylvia Owusu-Ansah, MD, MPH ^a,^⁎
^a Department of Pediatrics, Division of Pediatric Emergency Medicine, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA
^b Department of Pediatrics, Division of Pediatric Infectious Diseases, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA
^c Department of Pediatrics, Division of Child Neurology, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA
^d Department of Pediatric Radiology, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA
^e Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA
^f Family Medicine, UPMC St. Margaret, Pittsburgh, PA

^∗Corresponding Author.

Abstract

Acute flaccid myelitis is a debilitating illness characterized by acute onset of limb weakness, with one or more spinal segments displaying magnetic resonance imaging–confirmed gray matter lesions. Since the first outbreak in 2014, tracking by the Centers for Disease Control and Prevention has demonstrated biennial epidemics in the United States, with a current outbreak occurring in 2018. The cases of 3 children with acute flaccid myelitis who were initially thought to have common nonneurologic diagnoses are presented. Emergency physicians need to be vigilant to recognize the subtleties of acute flaccid myelitis because the illness progression is rapid and therapy is nuanced.

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	Supervising editor: Lise E. Nigrovic, MD, MPH. Specific detailed information about possible conflict of interest for individual editors is available at editors.
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	Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article as per ICMJE conflict of interest guidelines (see www.icmje.org). The authors have stated that no such relationships exist.

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Vol 74 - N° 4

P. 503-508 - octobre 2019 Retour au numéro

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New Cluster of Acute Flaccid Myelitis in Western Pennsylvania - 19/09/19

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