In Corsica, continental units (the Lower Units) affected by high-pressure metamorphism represent the remains of the European margin deformed during the Alpine orogeny. In order to document how Alpine deformation and metamorphism changed along the European margin involved in the Alpine subduction, we selected three key areas: the Corte, Cima Pedani, and Ghisoni transects. The three transects show a broadly similar lithostratigraphy. They are characterized by a Variscan basement intruded by Permo-Carboniferous metagranitoids, and by a sedimentary cover including Mesozoic carbonates and middle to late Eocene breccias and sandstones. The three transects recorded a similar deformation history with three deformation phases. Thermo-baric estimations, instead, reveal that each unit was exhumed along an independent retrograde path within the orogenic Alpine wedge. In particular, the lowest units of the Lower Units stack were exhumed along an isothermal path, whereas those located at upper structural levels experienced progressive heating.