Bacteria in Asthma Pathogenesis - 06/07/19
Doi : 10.1016/j.iac.2019.03.006
Michael Insel, MD a, Monica Kraft, MD b, ⁎ 
a Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of Arizona Health Sciences, University of Arizona College of Medicine – Tucson, 1501 North Campbell Avenue, PO Box 245017, Tucson, AZ 85724, USA
b Department of Medicine, College of Medicine Tucson, Asthma and Airway Disease Research Center, University of Arizona Health Sciences, University of Arizona College of Medicine – Tucson, 1501 North Campbell Avenue, PO Box 245017, Tucson, AZ 85724, USA
∗Corresponding author.
Résumé |
The airways are under continuous assault from aerosolized bacteria and oral flora. The bacteria present in the airways and gastrointestinal tract of neonates promote immune maturation and protect against asthma pathogenesis. Later bacterial infections and perturbations to the microbiome can contribute to asthma pathogenesis, persistence, and severity.
Le texte complet de cet article est disponible en PDF.Keywords : Asthma, Bacteria, Immunology, Microbiology
Plan
| Disclosure Statement: The authors have no commercial or financial conflicts of interest. |
© 2019
Elsevier Inc. Tous droits réservés.
Vol 39 - N° 3
P. 377-389 - août 2019 Retour au numéro
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