This paper describes some results from an experiment carried out regarding a procedure to be adopted for temperature and R.H. monitoring of indoor spaces designed for exhibiting events, such as museums and similar institutions. The monitored data employed in this study has been collected by the Department di Ricerche Energetiche ed Ambientali of the Università degli Studi di Palermo in co-operation with the Regional Gallery ''Palazzo Abatellis'' of Palermo. The study analyses a simple method for characterising the environmental quality of museums so as to ensure the optimal conservation of works of art. This methodology is based on the procedure (where thermal and hygrometry parameters are concerned) proposed by an Italian standard rule. A new technique, firstly applied to the industrial environment, based on the passive reactive monitoring of proper coupons is also proposed for monitoring air quality in museums. The methodology adopted, has been applied to two survey campaigns which were carried out at a distance of 5 years. This shows the two aspects of thermal-hygrometry and levels of indoor air quality aimed at preserving works of art. The future developments of this work are oriented towards the definition of guidelines in support of those responsible for the conservation of works of art and improvements in the quality of environments for artwork conservation and for the comfort of visitors through the use of proper HVAC systems.