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Age-Related Characteristics and Outcomes for Patients With Severe Trauma: Analysis of Japan’s Nationwide Trauma Registry - 22/02/19

Doi : 10.1016/j.annemergmed.2018.09.034 
Mitsuaki Kojima, MD, PhD a, Akira Endo, MD, PhD a, , Atsushi Shiraishi, MD, PhD a, b, Yasuhiro Otomo, MD, PhD a
a Trauma and Acute Critical Care Medical Center, Tokyo Medical and Dental University Hospital of Medicine, Bunkyo-ku, Tokyo, Japan 
b Emergency and Trauma Center, Kameda Medical Center, Kamogawa, Chiba, Japan 

Corresponding Author.

Abstract

Study objective

Although geriatric trauma patients are becoming more common, few large-scale analyses have comprehensively evaluated geriatric-specific characteristics in trauma. This study aims to clarify the age-specific characteristics, outcomes, and predictive accuracy of current trauma scoring systems among geriatric trauma patients.

Methods

Patients with severe trauma, with an Abbreviated Injury Scale score greater than or equal to 3, and registered in the Japan Trauma Data Bank during 2004 to 2015 were retrospectively reviewed. Age-related differences were assessed for injury mechanism, injured region, anatomic and physiologic severity, and inhospital mortality. The mortality risk was evaluated with multivariate mixed-effect models adjusted for Injury Severity Score, Revised Trauma Score, year of injury, and treating facility. Age-related differences in the accuracy of the Injury Severity Score and Revised Trauma Score for predicting inhospital mortality were evaluated with an area under the receiver operating characteristic curve.

Results

We identified 127,303 patients, including 67,316 geriatric patients (52.9%) who were aged 60 years or older. The percentage of geriatric patients increased from 31.9% to 59.7% during the study period. The most frequent injury mechanism was ground-level falls (55.2%) and the most frequently injured region was the pelvis and lower extremities (43.7%). Severity-adjusted mixed-effects models revealed a marked age-dependent increase in mortality. Although the Injury Severity Score had similar predictive accuracy among all generations, the accuracy of the Revised Trauma Score decreased with increasing age.

Conclusion

The characteristics of trauma patients varied widely according to age, and mortality risk increased steadily with increasing age, despite a decrease in anatomic injury severity. The Revised Trauma Score had decreasing predictive accuracy at older ages, suggesting that an alternative measure is needed.

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Plan


 Please see page 282 for the Editor’s Capsule Summary of this article.
 Supervising editor: Timothy F. Platts-Mills, MD, MSc
 Author contributions: MK and AE were responsible for drafting the article and for study supervision. All authors were responsible for revising the article and for interpretation of data, and accept responsibility for conduct of research and final approval. MK, AE, and AS were responsible for study concept and design and for statistical analysis. AE was responsible for obtaining funding. AS was responsible for acquisition of data. AE takes responsibility for the paper as a whole.
 All authors attest to meeting the four ICMJE.org authorship criteria: (1) Substantial contributions to the conception or design of the work; or the acquisition, analysis, or interpretation of data for the work; AND (2) Drafting the work or revising it critically for important intellectual content; AND (3) Final approval of the version to be published; AND (4) Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
 Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article as per ICMJE conflict of interest guidelines (see www.icmje.org/). The authors have stated that no such relationships exist. This work was supported by the Grants-in-Aid for Scientific Research (17K17045) from the Japan Society for the Promotion of Science.
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 A podcast for this article is available at www.annemergmed.com.


© 2018  American College of Emergency Physicians. Publié par Elsevier Masson SAS. Tous droits réservés.
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Vol 73 - N° 3

P. 281-290 - mars 2019 Retour au numéro
Article précédent Article précédent
  • Comparison of 30-Day Serious Adverse Clinical Events for Elderly Patients Presenting to the Emergency Department With Near-Syncope Versus Syncope
  • Aveh Bastani, Erica Su, David H. Adler, Christopher Baugh, Jeffrey M. Caterino, Carol L. Clark, Deborah B. Diercks, Judd E. Hollander, Susan E. Malveau, Bret A. Nicks, Daniel K. Nishijima, Manish N. Shah, Kirk A. Stiffler, Alan B. Storrow, Scott T. Wilber, Annick N. Yagapen, Robert E. Weiss, Benjamin C. Sun
| Article suivant Article suivant
  • The Applied Mathematics of the Geriatric Trauma Evaluation
  • Timothy F. Platts-Mills, Kristan Staudenmayer

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