Clear cell acanthoma (CCA)-like lesions of the nipple/areola: A clinicopathological study of 12 cases supporting a nonneoplastic eczematous disease - 11/02/19
Abstract |
Background |
Clear cell acanthoma (CCA) of the nipple/areola has been reported. The CCA-like histology more likely represents a feature of eczematous dermatitis of the nipple/areola.
Objective |
We reviewed cases of CCA-like lesions of the nipple/areola and compared them with classic CCA to clarify their relationship.
Methods |
The clinicopathological features of 12 cases of CCA-like lesions of the nipple/areola were compared with classic CCA. The literature on this condition was reviewed, and the results of various treatments were analyzed.
Results |
CCA-like lesions of the nipple/areola were clinically different from those of classic CCA. Although they shared the glycogen-rich clear epidermal cells with neutrophilic exocytosis, dermal eosinophils appeared to be a distinctive feature. The anatomic site and association with atopic dermatitis suggested that CCA-like lesions of nipple/areola might represent a manifestation of atopic eczema involving nipple/areola. Topical steroids could be effective.
Limitations |
This was a retrospective study with limited cases.
Conclusions |
Although CCA-like lesions of the nipple/areola shared histopathological features with classic CCA, their clinical changes were consistent with dermatitis. We propose to name this condition CCA-like eczematous dermatitis of the nipple/areola.
Le texte complet de cet article est disponible en PDF.Key words : areola, breast, clear cell acanthoma, dermoscope, eczema, nipple
Plan
| Funding sources: None. |
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| Conflicts of interest: None declared. |
Vol 80 - N° 3
P. 749-755 - mars 2019 Retour au numéro
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