Steroid Free Treatment of Autoimmune Hepatitis in Selected Children - 04/02/19
Doi : 10.1016/j.jpeds.2018.12.070
Andrew Wehrman, MD 1, ∗, Orith Waisbourd-Zinman, MD 1, 2, ∗, Amit Shah, MD 1, Didja Hilmara 3, Henry Lin, MD, MBA 1, Elizabeth B. Rand, MD 1, ⁎ 
1 Children's Hospital of Philadelphia, Division of Gastroenterology, Hepatology, and Nutrition, Philadelphia, PA
2 Schneider Children's Medical Center of Israel, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel
3 College of Arts and Sciences, University of Pennsylvania, Philadelphia, PA
∗Reprint requests: Elizabeth B. Rand, MD, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19104.Children's Hospital of Philadelphia3401 Civic Center BlvdPhiladelphiaPA19104
Sous presse. Épreuves corrigées par l'auteur.
Disponible en ligne depuis le Monday 04 February 2019
Abstract |
Current guidelines recommend steroids for induction of remission in all children diagnosed with autoimmune hepatitis regardless of the clinical presentation. In this report, we describe our experience in treating selected asymptomatic children with autoimmune hepatitis using a steroid-free regimen; this treatment strategy was safe and effective in inducing remission.
Le texte complet de cet article est disponible en PDF.Keywords : azathioprine, AIH, liver disease, pediatric, prednisone
Abbreviations : AIH, ANA, ANCA, ALT, LKM, SMA
Plan
| Funded by the Fred and Suzanne Biesecker Pediatric Liver Center and the NIH (Grant numbers NIH T32 HD 043021 and NIH T32 DK 101371 [to A.W.]). The authors declare no conflicts of interest. |
© 2019
Elsevier Inc. Tous droits réservés.
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