Effect of aging on blood pressure in Leh, Ladakh, a high-altitude (3524 m) community, by comparison with a Japanese town - 21/03/08
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Abstract |
The effect of aging on blood pressure (BP) and heart rate (HR) was investigated in a cross-sectional study in the high-altitude community of Leh, Ladakh (altitude: 3524 m) and a Japanese community in U town, Hokkaido (altitude: 25 m). BP and HR were obtained in a sitting position from 332 subjects 13–81 years of age in Ladakh, and from 216 Japanese citizens, 24–79 years of age. Measurements were taken after a 2-min rest, using a semi-automated BP device (UA-767 PC, A&D Co. LTD, Tokyo). High-altitude people showed higher diastolic BP and HR values than lowland people (83.2 vs. 76.9 mmHg and 78.6 vs. 69.2 bpm, P < 0.001), but no difference in systolic BP. Highland people also showed a steeper BP increase with age than the lowland people (systolic BP: 0.7476 vs. 0.3179 mmHg/year, P < 0.0005; diastolic BP: 0.3196 vs. 0.0750 mmHg/year, P < 0.001). This chronoecologic investigation in Ladakh examined the circulation as a physiological system at high-altitude. Our data indicate the need for a more comprehensive cardiovascular assessment for a better diagnosis and a more fruitful treatment. Longitudinal observations of effects of socio-ecologic factors on the cardiovascular system should help prevent strokes and other cardiovascular events, especially at high altitude.
Le texte complet de cet article est disponible en PDF.Keywords : Aging, Blood pressure, High-altitude community, Comprehensive cardiovascular assessment
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Vol 59 - N° S1
P. 54-57 - janvier-février 2005 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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