Significance of bile duct resection for advanced gallbladder cancer without biliary infiltration - 06/12/18
, Atsushi Nanashima, Masahide Hiyoshi, Naoya Imamura, Koichi Yano, Takeomi HamadaAbstract |
Background |
Although hepatectomy IVa + V with bile duct resection (BDR) for T2 gallbladder cancer (GBC) is performed in our institution, limited surgery is occasionally selected. This study aimed to clarify the significance of BDR for advanced GBC without biliary infiltration.
Methods |
Sixty-seven patients were enrolled who underwent surgery for pT2 or higher GBC without biliary infiltration. The patient disposition, demographics, clinicopathologic factors, disease-free survival (DFS) and overall survival (OS) were compared between the BDR group (n = 33) and non-BDR group (n = 34).
Results |
There were no significant differences in TNM factors, R0 rate, morbidity rate and rate of adjuvant chemotherapy between the two groups. The patients in the BDR group were significantly younger, had more lymph nodes harvested than those in the non-BDR group, and more frequently underwent hepatectomy IVa + V and extended lymphadenectomy. There were no significant differences in the OS and DFS rates between the two groups.
Conclusion |
The significance of BDR for pT2 or higher advanced GBC without biliary infiltration was equivocal because the patients received no survival benefit by undergoing BDR.
Le texte complet de cet article est disponible en PDF.Highlights |
• | Extensive surgery was frequently performed in resecting the bile duct for gallbladder cancer without biliary infiltration. |
• | The significance of bile duct resection was equivocal because no survival benefit was identified in our study. |
• | Our study can contribute to the decision of selecting the optimal surgery for the old patients with multiple comorbidities. |
Keywords : Bile duct resection, Gallbladder cancer, Biliary infiltration
Plan
Vol 216 - N° 6
P. 1122-1126 - décembre 2018 Retour au numéro
Article précédent
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