Jakinibs for the treatment of immune dysregulation in patients with gain-of-function signal transducer and activator of transcription 1 (STAT1) or STAT3 mutations - 06/11/18
Doi : 10.1016/j.jaci.2018.07.020
Lisa R. Forbes, MD a, b 
, Tiphanie P. Vogel, MD, PhD a, b, Megan A. Cooper, MD, PhD c, Johana Castro-Wagner, MD d, Edith Schussler, MD e, ∗, Katja G. Weinacht, MD, PhD f, Ashley S. Plant, MD g, Helen C. Su, MD, PhD h, Eric J. Allenspach, MD, PhD i, Mary Slatter, MD j, Mario Abinun, MD j, Desa Lilic, MD j, Charlotte Cunningham-Rundles, MD, PhD e, Olive Eckstein, MD k, Peter Olbrich, MD l, m, R. Paul Guillerman, MD n, Niraj C. Patel, MD o, Yesim Y. Demirdag, MD p, Christa Zerbe, MD h, Alexandra F. Freeman, MD h, Steven M. Holland, MD h, Paul Szabolcs, MD q, Andrew Gennery, MD j, Troy R. Torgerson, MD, PhD i, Joshua D. Milner, MD l, Jennifer W. Leiding, MD d, r
, Tiphanie P. Vogel, MD, PhD a, b, Megan A. Cooper, MD, PhD c, Johana Castro-Wagner, MD d, Edith Schussler, MD e, ∗, Katja G. Weinacht, MD, PhD f, Ashley S. Plant, MD g, Helen C. Su, MD, PhD h, Eric J. Allenspach, MD, PhD i, Mary Slatter, MD j, Mario Abinun, MD j, Desa Lilic, MD j, Charlotte Cunningham-Rundles, MD, PhD e, Olive Eckstein, MD k, Peter Olbrich, MD l, m, R. Paul Guillerman, MD n, Niraj C. Patel, MD o, Yesim Y. Demirdag, MD p, Christa Zerbe, MD h, Alexandra F. Freeman, MD h, Steven M. Holland, MD h, Paul Szabolcs, MD q, Andrew Gennery, MD j, Troy R. Torgerson, MD, PhD i, Joshua D. Milner, MD l, Jennifer W. Leiding, MD d, r a Division of Allergy, Immunology and Rheumatology, Department of Pediatrics, Baylor College of Medicine, Houston, Tex
b Center for Human Immunobiology, Texas Children's Hospital, Houston, Tex
c Department of Pediatrics, Division of Rheumatology, Washington University, St Louis, Mo
d Division of Allergy and Immunology, Department of Pediatrics, University of South Florida, St Petersburg, Fla
e Division of Allergy and Immunology and Department of Medicine and Pediatrics, The Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY
f Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford School of Medicine, Stanford, Calif
g Department of Pediatric Oncology, Children's Hospital of Orange County, Orange, Calif
h Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md
i Division of Rheumatology, Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, Wash
j Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation and Primary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle upon Tyne University, United Kingdom
k Department of Hematology and Oncology, Texas Children's Cancer Center, Houston, Tex
l Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md
m Department of Pediatric Infectious Diseases and Immunopathologies, Institute of Biomedicine Seville (IBiS), University Hospital Virgen del Rocio, Seville, Spain
n Department of Pediatric Radiology, Texas Children's Hospital and Department of Radiology, Baylor College of Medicine, Houston, Tex
o Department of Pediatrics, Section of Infectious Disease and Immunology, Levine Children's Hospital, Atrium Health, Charlotte, NC
p Department of Pediatrics, Division of Pediatric Allergy and Immunology, College of Physcians and Surgeons of Columbia Univeristy, New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY
q Division of Blood and Marrow Transplantation and Cellular Therapies, University of Pittsburgh, Pittsburgh, Pa
r Cancer and Blood Disorders Institute, Johns Hopkins-All Children's Hospital, St Petersburg, Fla
| Supported in part by the Intramural Research Program of the National Institutes of Health, National Institute of Allergy and Infectious Diseases. |
|
| Disclosure of potential conflict of interest: The authors declare that they have no relevant conflicts of interest. |
© 2018
American Academy of Allergy, Asthma & Immunology. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 142 - N° 5
P. 1665-1669 - novembre 2018 Retour au numéro
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