Endogenous bradykinin and B1-B5 during angiotensin-converting enzyme inhibitor–associated angioedema - 06/11/18
Doi : 10.1016/j.jaci.2018.06.037
Scott A. Hubers, MD a, Kevin Kohm, MS a, Shouzuo Wei, PhD a, Chang Yu, PhD b, Hui Nian, PhD b, Ryan Grabert, AM c, Daniel J. Sexton, PhD c, Nancy J. Brown, MD a 
a Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn
b Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tenn
c Global Nonclinical Development, Shire, Lexington, Mass
| Supported by grants from the National Institutes of Health (R01-HL-125426) and by a grant from Shire HGT. Kininogen measurements were performed at Shire. |
|
| Disclosure of potential conflict of interest: D. J. Sexton is employed by and has stock in Shire. N. J. Brown serves as a consultant to Shire HGT, Novartis Pharmaceuticals, Viamet Pharmaceuticals, and Alnylam Pharmaceuticals and has stock/stock options with Alnylam. The rest of the authors declare that they have no relevant conflicts of interest. |
© 2018
American Academy of Allergy, Asthma & Immunology. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 142 - N° 5
P. 1636 - novembre 2018 Retour au numéro
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