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Long-Term Academic Functioning Following Cogmed Working Memory Training for Children Born Extremely Preterm: A Randomized Controlled Trial - 23/10/18

Doi : 10.1016/j.jpeds.2018.07.003 
Peter J. Anderson, PhD 1, 2, * , Katherine J. Lee, PhD 2, 3, Gehan Roberts, MPH, PhD 2, 3, Megan M. Spencer-Smith, PhD 1, 2, Deanne K. Thompson, PhD 2, 3, 4, Marc L. Seal, PhD 2, 3, Chiara Nosarti, PhD 5, Andrea Grehan, MSc 2, Elisha K. Josev, PhD 2, 3, Susan Gathercole, PhD 6, Lex W. Doyle, MD, MSc, FRACP 2, 3, 7, 8, Leona Pascoe, BBNSc (Hons), GDipPsych 1, 2
1 Monash Institute of Cognitive and Clinical Neurosciences, School of Psychological Sciences, Monash University, Melbourne, Australia 
2 Murdoch Children's Research Institute, Melbourne, Australia 
3 Department of Pediatrics, The University of Melbourne, Melbourne, Australia 
4 Florey Institute of Neuroscience and Mental Health, Melbourne, Australia 
5 King's College London, London, England, United Kingdom 
6 University of Cambridge, Cambridge, England, United Kingdom 
7 Neonatal Services, The Royal Women's Hospital, Melbourne, Australia 
8 Department of Obstetrics and Gynecology, The University of Melbourne, Melbourne, Australia 

*Reprint requests: Peter J. Anderson, PhD, Monash Institute of Cognitive and Clinical Neurosciences, School of Psychological Sciences, Monash University, 18 Innovation Walk, Clayton Campus, Clayton, VIC 3800, Australia.Monash Institute of Cognitive and Clinical NeurosciencesSchool of Psychological SciencesMonash University18 Innovation WalkClayton CampusClaytonVIC3800Australia

Abstract

Objective

To assess the effectiveness of Cogmed Working Memory Training compared with a placebo program in improving academic functioning 24 months post-training in extremely preterm/extremely low birth weight 7-year-olds.

Study design

A multicenter double-blind, placebo-controlled randomized controlled trial was conducted across all tertiary neonatal hospitals in the state of Victoria, Australia. Participants were 91 extremely preterm/extremely low birth weight 7-year-old children born in Victoria in 2005. Children were randomly assigned to either the Cogmed or placebo arm and completed the Cogmed or placebo program (20-25 sessions of 35-40 minutes duration) at home over 5-7 weeks. Academic achievement (word reading, spelling, sentence comprehension, and mathematics) was assessed 24 months post-training, as well as at 2 weeks and 12 months post-training, via standardized testing inclusive of working memory, attention, and executive behavior assessments. Data were analyzed using an intention-to-treat approach with mixed-effects modeling.

Results

There was little evidence of any benefits of Cogmed on academic functioning 24 months post-training, as well as on working memory, attention, or executive behavior at any age up to 24 months post-training compared with the placebo program.

Conclusions

We currently do not recommend administration of Cogmed for early school-aged children born extremely preterm/extremely low birth weight to improve academic functioning.

Trial registration

Australian New Zealand Clinical Trials Registry: ACTRN12612000124831.

Le texte complet de cet article est disponible en PDF.

Keywords : cognitive training, prematurity, academic outcomes

Abbreviations : ELBW


Plan


 Funded by the National Health and Medical Research Council (NHMRC: Project Grant 1028422, Centre of Research Excellence in Newborn Medicine (1060733), Program Grant 606789, Senior Research Fellowship 1081288, Career Development Fellowship 1085754), Monash University and the Murdoch Children's Research Institute. The authors declare no conflicts of interest.


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Vol 202

P. 92 - novembre 2018 Retour au numéro
Article précédent Article précédent
  • Language Trajectories of Children Born Very Preterm and Full Term from Early to Late Childhood
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