Pediatric extracorporeal cardiopulmonary resuscitation settled in an emergency department for a propafenone intentional intoxication - 15/10/18

Doi : 10.1016/j.ajem.2018.08.001

Marco Marano, MD ^a, Bianca M. Goffredo, MD ^b, Mara Pisani, MD ^a, Sergio Filippelli, MD ^c, Corrado Cecchetti, MD ^a, Fabrizio Drago, MD ^c, Maria A. Barbieri, MD ^a, Joseph Nunziata, MD ^a, Leonardo Genuini, MD ^a, Matteo Di Nardo, MD ^a,^{^⁎}
^a Emergency Department, IRCCS, Children's Hospital Bambino Gesù, IRCCS, Rome, Italy
^b Laboratory of Analytical Biochemistry, IRCCS, Bambino Gesù Children Hospital, IRCCS, Rome, Italy
^c Department of Pediatric Cardiology and Cardiac Surgery, Children's Hospital Bambino Gesù, Rome, Italy

^⁎Corresponding author at: Emergency Department, Children's Hospital Bambino Gesù, IRCCS, Rome, Italy.Emergency DepartmentChildren's Hospital Bambino Gesù, IRCCSRomeItaly

Abstract

The use of drugs in suicide attempts is becoming more and more frequent among adolescents. Intentional intoxication with propafenone is very rare and mainly reported in adults associated with other drugs. The therapeutic approach is symptomatic, since there is no specific antidote for propafenone. We present a pediatric case of intentional ingestion of 1.8 g of propafenone that caused refractory cardiogenic shock. The patient was successfully rescued with extracorporeal cardiopulmonary resuscitation in the emergency department of a secondary level peripheral hospital.

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Keywords : Intoxication, Pediatrics, Extracorporeal cardiopulmonary resuscitation

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The authors of this manuscript have nothing to disclose concerning possible financial or personal relationships with commercial entities that may have a direct or indirect interest in the subject matter of this document. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. All authors had full freedom to explore the data and analyze results independently. All authors are aware of content presented here and had authority in the final decision to submit material for publication.

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Vol 36 - N° 11

P. 2132.e1-2132.e3 - novembre 2018 Retour au numéro

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Pediatric extracorporeal cardiopulmonary resuscitation settled in an emergency department for a propafenone intentional intoxication - 15/10/18

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