Eosinophilic Esophagitis in Children and Adults - 18/09/18

Doi : 10.1016/j.giec.2017.07.004

Jonathan E. Markowitz, MD, MSCE ^a,^⁎ , Steven B. Clayton, MD ^b
^a Pediatric Gastroenterology and Nutrition, Children’s Hospital of Greenville Health System, University of South Carolina School of Medicine-Greenville, 200 Patewood Drive, Suite A-140, Greenville, SC 29615, USA
^b Gastroenterology and Liver Center, Greenville Health System, University of South Carolina School of Medicine-Greenville, 890 West Faris Road, Suite 100, Greenville, SC 29605, USA

^∗Corresponding author.

Résumé

Adults and children with eosinophilic esophagitis (EoE) have distinct clinical and endoscopic presentations. Recognition of clinical signs, along with laboratory and endoscopic findings, is critical for the identification of patients with EoE because delay in diagnosis has been associated with esophageal remodeling and stricture formation. Clinical presentation varies considerably between adults and children. This is less due to differences in the disease and more due to patient differences. This article describes the similarities and differences in clinical presentation of children and adults with EoE, including areas of epidemiology, clinical and endoscopic presentation, pathophysiology, and treatment.

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Keywords : Eosinophilic esophagitis, Children, Adults, Clinical features, Treatment, Diet therapy, Dilation