A kindred with mutant IKAROS and autoimmunity - 04/08/18

Doi : 10.1016/j.jaci.2018.04.008

Erika Van Nieuwenhove, MD ^a,^b,^c, Josselyn E. Garcia-Perez, PhD ^a,^b, Christine Helsen, PhD ^d, Princess D. Rodriguez, MSc ^e, Pauline A. van Schouwenburg, PhD ^f, James Dooley, PhD ^a,^b, Susan Schlenner, PhD ^a,^b, Mirjam van der Burg, PhD ^f, Els Verhoeyen, PhD ^g,^h, Rik Gijsbers, PhD ^i,^j, Seth Frietze, PhD ^e, Hilde Schjerven, PhD ^k, Isabelle Meyts, MD, PhD ^a,^c, Frank Claessens, PhD ^d, Stephanie Humblet-Baron, MD, PhD ^a,^b,^{^{∗
These authors contributed equally to this work.}}, Carine Wouters, MD, PhD ^a,^c,^{^{∗
These authors contributed equally to this work.}} , Adrian Liston, PhD ^a,^b,^{^{∗
These authors contributed equally to this work.}}
^a Department of Microbiology and Immunology, KUL - University of Leuven, Leuven, Belgium
^b VIB Center for Brain and Disease Research, Leuven, Belgium
^c University Hospitals Leuven, Leuven, Belgium
^d Department of Cellular and Molecular Medicine, KUL - University of Leuven, Leuven, Belgium
^e Department of Medical Laboratory and Radiation Science, University of Vermont, Burlington, Vt
^f Department of Immunology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
^g CIRI – International Center for Infectiology Research, Team EVIR, Inserm, Université Claude Bernard Lyon 1, Ecole Normale Supérieure de Lyon, Univ Lyon, Lyon, France
^h Université Côte d’Azur, INSERM, C3M, Nice, France
ⁱ the Laboratory for Viral Vector Technology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium
^j Leuven Viral Vector Core, Leuven, Belgium
^k the Department of Laboratory Medicine, University of California, San Francisco, Calif

This work was supported by the European Research Council grant IMMUNO and the KU Leuven (GOA). E.V.N. (1S22716N) and S.H.-B. (1272517N) are Fonds voor Wetenschappelijk Onderzoek (FWO) fellows. Part of this work was supported by the Dutch Organisation for Scientific Research (Nederlandse Organisatie voor Wetenschappelijk Onderzoek/Zorgonderzoek en Medische wetenschappen VIDI grant no. 91712323 to M.B., VENI grant no. 91616058 to P.A.S.) and by an Institutional Research Grant from the American Cancer Society (grant no. 14-196-01 to S.F.).

Disclosure of potential conflict of interest: H. Schjerven is an Arthritis National Research Foundation Scholar and a Hellman Fellow. The rest of the authors declare that they have no relevant conflicts of interest.

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Vol 142 - N° 2

P. 699 - août 2018 Retour au numéro

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