Rapid Fire: Acute Blast Crisis/Hyperviscosity Syndrome - 22/07/18
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Résumé |
Emergency providers are likely to encounter patients with acute and chronic leukemias. In some cases, the first presentation to the emergency department may be for symptoms related to blast crisis and leukostasis. Making a timely diagnosis and consulting a hematologist can be life saving. Presenting symptoms are caused by complications of bone marrow infiltration and hyperleukocytosis with white blood cell counts over 100,000. Presentations may include fatigue (anemia), bleeding (thrombocytopenia), shortness of breath, and/or neurologic symptoms owing to hyperleukocytosis and subsequent leukostasis. Treatment of symptomatic cases involves induction chemotherapy and/or leukapheresis. Asymptomatic hyperleukocytosis can be treated with hydroxyurea.
Le texte complet de cet article est disponible en PDF.Keywords : Blast, Leukostasis, Leukapheresis, Petechiae, Hyperviscosity, Chronic myeloid leukemia, Acute myeloid leukemia, Hydroxyurea
Plan
Disclosure Statement: The authors have no disclosures. |
Vol 36 - N° 3
P. 603-608 - août 2018 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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