Generation of adult human T-cell progenitors for immunotherapeutic applications - 05/04/18

Doi : 10.1016/j.jaci.2017.10.034

Laura Simons, MD, PhD ^a,^b,^{∗
These authors contributed equally to this work as co-first authors.}, Kuiying Ma, MSc ^a,^b,^{∗
These authors contributed equally to this work as co-first authors.}, Corinne de Chappedelaine, PhD ^a,^b, Ranjita Devi Moiranghtem, PhD ^a,^b, Elodie Elkaim, MD ^a,^b, Juliette Olivré, Bc ^a,^b, Sandrine Susini, PhD ^a,^b, Kevin Appourchaux, PhD ^a,^b, Christian Reimann, MD, PhD ^a,^b,^c, Hanem Sadek, MSc ^a,^b, Olivier Pellé, MSc ^d, Nicolas Cagnard, MSc ^e, Elisa Magrin, MD ^f, Chantal Lagresle-Peyrou, PhD ^a,^b,^f, Tom Taghon, PhD ^g, Antonio Rausell, PhD ^b,^h, Marina Cavazzana, MD, PhD ^a,^b,^f, Isabelle André-Schmutz, PhD ^a,^b,^f
^a Human Lymphohaematopoiesis Laboratory, INSERM U1163, Paris, France
^b University of Paris Descartes-Sorbonne Paris Cité, IMAGINE Institute, Paris, France
^c Department of Oncology/Hematology, Children's Hospital, Cantonal Hospital Lucerne, Lucerne, Switzerland
^d Cytometry Platform of SFR Necker, Inserm US24-CNRS UMS 3633, Paris, France
^e Bio-informatic Plateform, University of Paris Descartes-Sorbonne Paris Cité, INSERM US24/CNRS, UMS3633, Paris, France
^f Biotherapy Clinical Investigation Centre, Necker Children's Hospital, Paris, France
^g Department of Clinical Chemistry, Microbiology and Immunology, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
^h Clinical Bioinformatics Laboratory, IMAGINE Institute, Paris, France

Supported by the French National Institute of Health and Medical Research (INSERM), a European Research Council grant (ERC Regenerative Therapy, 269037), a European Union FP7 grant (CELL-PID, 261387), a European Union H2020 grant (SCIDNet, 666908), the Imagine Institute, an INCA-Plan Cancer grant (2009-2013), and a public grant overseen by the French National Research Agency (ANR) as part of the program “Investissements d'Avenir” (reference: ANR-10-IAHU-01). K.M. was funded by a China Scholarship Council (CSC). E.E. was funded by an INSERM-Plan Cancer fellowship. C.R. was funded by postdoctoral scholarships from the Deutsche Forschungsgemeinschaft (DFG). T.T. was funded by the Fund for Scientific Research Flanders (FWO Vlaanderen research projects G0B2913N). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Disclosure of potential conflict of interest: C. Reimann's institution has received travel support from Bayer. The rest of the authors declare that they have no relevant conflicts of interest.

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Vol 141 - N° 4

P. 1491 - avril 2018 Retour au numéro

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