Haploinsufficiency of A20 causes autoinflammatory and autoimmune disorders - 05/04/18
Doi : 10.1016/j.jaci.2017.10.039
Tomonori Kadowaki, MD a, ∗, Hidenori Ohnishi, MD, PhD a, ∗, Norio Kawamoto, MD, PhD a, Tomohiro Hori, MD, PhD a, Kenichi Nishimura, MD b, Chie Kobayashi, MD, PhD c, Tomonari Shigemura, MD, PhD d, Shohei Ogata, MD, PhD e, Yuzaburo Inoue, MD, PhD f, Tomoki Kawai, MD, PhD g, Eitaro Hiejima, MD, PhD g, Masatoshi Takagi, MD, PhD h, Kohsuke Imai, MD, PhD h, Ryuta Nishikomori, MD, PhD g, Shuichi Ito, MD, PhD b, Toshio Heike, MD, PhD g, Osamu Ohara, PhD i, Tomohiro Morio, MD, PhD j, Toshiyuki Fukao, MD, PhD a 
, Hirokazu Kanegane, MD, PhD j
, Hirokazu Kanegane, MD, PhD j a Department of Pediatrics, Gifu University Graduate School of Medicine, Gifu, Japan
b Department of Pediatrics, Yokohama City University, Yokohama, Kanagawa, Japan
c Department of Child Health, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
d Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan
e Department of Pediatrics, Kitasato University Hospital, Sagamihara, Kanagawa, Japan
f Department of Pediatrics, Eastern Chiba Medical Center, Chiba, Japan
g Department of Pediatrics, Kyoto University Hospital, Kyoto, Japan
h Department of Community Pediatrics, Perinatal and Maternal Medicine Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
i Department of Technology Development, Kazusa DNA Research Institute, Chiba, Japan
j Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
| This work was supported by Health and Labour Sciences Research Grants for Research on Intractable Diseases from the Ministry of Health, Labour and Welfare of Japan (grant nos. 17933688 and 17933299). |
|
| Disclosure of potential conflict of interest: H. Ohnishi has received Health and Labour Sciences Research Grants. K. Imai has received a grant from the Japanese Ministry of Health, Labour and Welfare and Sony, Inc; has consultant arrangements with CSL Behring KK and Novartis Pharma KK; and has received payment for lectures from CLS Behring and the Japan Blood Products Organization. R. Nishikomori has received payment for lectures from Novartis, Inc. S. Ito has received grants from Astellas Pharma, Inc, Pfizer Japan, Inc, AbbVie GK, Eisai Co Ltd, Sumitomo Dainipponn Pharma Co Ltd, Merck Sharp & Dohme, CSL Behring, and Kyowa Hakko Kirin Co Ltd and has received payment for lectures from Astellas Pharma, Inc, Pfizer Japan, Inc, Sanofi, AbbVie GK, Eisai Co Ltd, Asahi Kasei Parma Corporation, Sumitomo Dainipponn Pharma Co Ltd, Mitsubishi Tanabe Pharma Corporation, and Zenyaku Kogyo Co Ltd. T. Heike has received a grant from the Ministry of Health, Labour, and Welfare. O. Ohara has received a grant from the Jeffrey Modell Foundation. T. Morio has received consultant fees from Novartis, Chugai Pharmaceutical, and Teijin Pharma; has received grants from Asteras, CSL Behring, and Pfizer; and has received payment for lectures from Asteras, AbbVie, CSL Behring, Dainippon Sumitomo Pharmaceutical, JBPO, Tanabe Mitsubishi Pharmaceutical, and Teijin Pharma. T. Fukao has received grants from the Japan Agency for Medical Research and Development, Health and Labour Sciences Research Grants, Sanofi, Pfizer Japan, Inc, Chugai Pharm, Astellas, and Eli Lilly Japan KK. The rest of the authors declare that they have no relevant conflicts of interest. |
© 2017
American Academy of Allergy, Asthma & Immunology. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 141 - N° 4
P. 1485 - avril 2018 Retour au numéro
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