The aim of this study was to compare two initial arch wires, 0.014″ A-NiTi and 0.016″ Heat Activated NiTi (HANT), for amount of tooth alignment and perception of pain.

In total, 59 orthodontic patients (21 males and 38 females) from three orthodontic clinics participated in this 2-arm, parallel-group clinical trial and were randomized to 0.014″ A-NiTi (n=30) or 0.016″ HANT groups (n=29). Patient recruitment commenced in April 2016 and ended in December 2016. Age of the patients was between 12 to 25 years with an average of 17.92±3.74 years. Eligibility criteria included permanent dentition, non-extraction treatment plan in lower arch, Irregularity Index>2 in lower arch, no systemic disease influencing pain, no chronic Non Steroid Anti Inflammatory Drug (NSAID) therapy, and no history of dental pain, mucosal ulcers or temporomandibular disorders (TMD). Blinding was applicable to the patients and outcome assessment. The primary outcome was to compare the reduction of the Irregularity Index mean from bonding sessions to 4 weeks later in these groups and the secondary outcome was evaluation of the pain according to the modified McGill Pain Questionnaire (MPQ) with Visual Analogue Scale questionnaire (VAS).

The mean differences of irregularity indices between the two groups are not statistically significant (95% CI: 0.39–1.03; P=0.36) and according to the questionnaire, there was no significant difference between the two groups in trigger, site, description, duration, beginning, medication, and pain reduction over time. However, the VAS scale of HANT group was significantly higher than that of A-NiTi (P=0.04).

Results from this investigation suggested that there was no clinical difference in amount of tooth alignment and perception of pain between 0.014″ A-NiTi and 0.016″ HANT wires.