Disparities in compliance with the Oncotype DX breast cancer test in the United States: A National Cancer Data Base assessment - 20/03/18
, Ammar Hashmi , James Dove , Marie Hunsinger , Tania Arora , Jeffrey Wild , Mohsen Shabahang , Joseph Blansfield ⁎ Abstract |
Background |
Oncotype DX (ODX) is a multi-gene tumor assay for breast cancer patients. Our objective is to assess whether eligible ODX patients received the test and whether recommendations were followed based on respective risk.
Methods |
We retrospectively analyzed testing in patients deemed eligible for ODX using the National Cancer Data Base.
Results |
A total of 158,235 patients met ODX eligibility criteria. Sixty-four percent of eligible patients did not receive the test. Non-testing rose with age. White patients were more likely to be tested (56%) versus black patients (46%, p < 0.0001). Testing was highest at academic facilities (40%). Privately insured patients were more likely to get the test compared to uninsured (45 versus 34%, p < 0.0001). Those in the highest income quartile were more likely to be tested (p < 0.001).
Conclusions |
ODX is under-utilized, with racial and socio-economic factors influencing testing. Further studies are necessary to identify ways to remove disparities and increase testing when appropriate.
Le texte complet de cet article est disponible en PDF.Keywords : Oncotype DX, Breast cancer, Compliance, Disparities
Plan
Vol 215 - N° 4
P. 686-692 - avril 2018 Retour au numéro
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