Burn patients with infection-related ventilator associated complications have worse outcomes compared to those without ventilator associated events - 20/03/18

Doi : 10.1016/j.amjsurg.2017.10.034

Duraid Younan ^a,^⁎ , Russell Griffin ^b, Ahmed Zaky ^c, Jean-Francois Pittet ^c, Bernard Camins ^d
^a Division of Acute Care Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, United States
^b Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, United States
^c Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, AL, United States
^d Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States

^∗Corresponding author. Division of Acute Care Surgery, University of Alabama at Birmingham, 701 19th Street S, LHRB #112, Birmingham, AL, 35294, United States.Division of Acute Care SurgeryUniversity of Alabama at Birmingham701 19th Street SLHRB #112BirminghamAL35294United States

Abstract

Background

The Centers for Disease Control and Prevention (CDC) replaced its definition for ventilator-associated pneumonia (VAP) in 2013. The aim of the current study is to compare the outcome of burn patients with ventilator associated events (VAEs).

Methods

Burn patients with at least two days of ventilator support were identified from the registry between 2013 and 2016. Kruskal-Wallis and Fisher's exact tests were utilized for continuous and categorical variables, respectively. A logistic regression was used for the association between VAE and in-hospital mortality.

Results

243 patients were admitted to our burn center, of whom 208 had no VAE, 8 had a VAC, and 27 had an IVAC or PVAP. There was no difference in hospital length of stay, ICU length of stay and ventilator support days between those with no VAE and a VAC. Those with IVAC-plus had significantly worse outcomes compared to patients with no VAEs.

Conclusions

Burn patients with IVAC-plus had significantly longer hospital and ICU lengths of stay, days on ventilator compared with patients with no VAEs.

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Keywords : Ventilator associated condition, Infection-related ventilator associated complication, Burn

Plan

Introduction

Materials and methods

Study design and variable definitions

Conflict of interest and source of funding for ALL authors

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Vol 215 - N° 4

P. 678-681 - avril 2018 Retour au numéro

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Burn patients with infection-related ventilator associated complications have worse outcomes compared to those without ventilator associated events - 20/03/18

Abstract

Background

Methods

Results

Conclusions

Plan

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