Early seasonal influenza vaccination and delayed influenza peaks – A possible cause of end-of-season outbreaks - 20/12/17
Doi : 10.1016/j.jinf.2017.08.002
Julian W. Tang * 
Clinical Microbiology, University Hospitals of Leicester, NHS Trust, Leicester, UK
Infection, Immunity, Inflammation, University of Leicester, Leicester, UK
*Corresponding author. Clinical Microbiology, University Hospitals of Leicester NHS Trust, Level 5 Sandringham Building, Leicester Royal Infirmary, Infirmary Square, Leicester LE1 5WW, UK. Fax: +44 0116 255 1949.Clinical MicrobiologyUniversity Hospitals of Leicester NHS TrustLevel 5 Sandringham BuildingLeicester Royal InfirmaryInfirmary SquareLeicesterLE1 5WWUK
Juliette Mutuyimana
Clinical Microbiology, University Hospitals of Leicester, NHS Trust, Leicester, UK
Kah Wee Teo, Sarah Lea
Adult Cystic Fibrosis Unit, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK
Bernadette Donaghy
Adult Cystic Fibrosis Unit, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK
Janice Blount
Infection Prevention and Control, University Hospitals of Leicester, NHS Trust, Leicester, UK
Simon Range
Adult Cystic Fibrosis Unit, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK
Highlights |
• | Intra-seasonal waning of influenza vaccine-induced immunity is now well-recognised. |
• | Late seasonal influenza incidence is regular and predictable in some populations. |
• | Despite a good vaccine match this may lead to end-of-season influenza outbreaks. |
• | Later-in-the-season influenza immunisation may reduce outbreaks in such populations. |
Keywords : Influenza, Vaccine, Waning, Immunity, Late, Seasonal, Incidence
Plan
© 2017
The British Infection Association. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 76 - N° 1
P. 96-98 - janvier 2018 Retour au numéro
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