Low birth weight and morbidity from diarrhea and respiratory infection in northeast Brazil - 12/10/17
Abstract |
OBJECTIVE: To compare morbidity and mortality rates of low birth weight (LBW) and appropriate birth weight infants born at term, focusing on diarrheal and respiratory infections. STUDY DESIGN: A cohort of 133 LBW infants (1500 to 2499 gm) and 260 appropriate birth weight infants (3000 to 3499 gm), individually matched by sex and season of birth, were followed for the first 6 months of life. None had congenital anomalies and all were from poor families living in the interior of Pernambuco, northeast Brazil. Data on infant deaths, hospitalizations, and morbidity were collected prospectively through daily home visits (except Sundays) from birth through week 8, then twice weekly for weeks 9 to 26. The effects of birth weight were assessed with a variety of multivariable techniques, controlling for confounders. RESULTS: Of the LBW infants, 56% were wasted (thin), 23% were stunted, and 17% were both wasted and stunted. The LBW infants (median 2380 gm) experienced a sevenfold higher mortality rate and fourfold higher rate of hospitalization than appropriate birth weight infants. Almost all deaths and hospitalizations were in the postneonatal period. The LBW infants also experienced 33% more days with diarrhea and 32% more days with vomiting (p = 0.003 in each case). The prevalences of cough and fever were not significantly different. CONCLUSIONS: Infant deaths, hospitalizations, and diarrheal morbidity are increased in term LBW infants who have only a modest weight deficit. (J PEDIATR 1996;128:497-504)
Le texte complet de cet article est disponible en PDF.Abbreviations : ABW, LBW
Plan
From the Centre for Human Nutrition, Department of Public Health and Policy, and the Maternal and Child Epidemiology Unit, Department of Epidemiology and Population Sciences, London School of Hygiene and Tropical Medicine, London, United Kingdom, and the Department of Nutrition, Centre for Health Sciences, Federal University of Pernambuco, Recife-PE, Brazil |
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Supported by The Wellcome Trust, United Kingdom (grant No. 036605/Z/92). Dr. Pedro Lira received financial support from Fundação Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Brazil. |
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Reprint requests: Ann Ashworth, BSc, PhD, Centre for Human Nutrition, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, United Kingdom. |
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0022-3476/96/$5.00 + 0 9/20/71215 |
Vol 128 - N° 4
P. 497-504 - avril 1996 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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