Chemical ablation of ventricular tachycardia in the dog - 12/10/17
Abstract |
Sustained ventricular tachycardia was induced in dogs following occlusion-reperfusion of the left anterior descending coronary artery. While dogs were supported by cardiopulmonary bypass, the left ventricle was opened and the endocardium was mapped during electrically induced ventricular tachycardia to determine the earliest site of ventricular activation. Phenol (carbolic acid) application at that site necrosed myocardium to a depth of 1 to 3 mm and prevented electrical reinduction of ventricular tachycardia in 9 of 15 dogs. These data suggest that chemical ablation may be used as an alternate means to destroy areas of myocardium involved in the genesis or maintenance of ventricular tachycardia, particularly if these areas cannot be resected surgically because of their size or location.
Le texte complet de cet article est disponible en PDF.| ☆ | This study was supported in part by the Herman C. Krannert Fund; by Grants HL-06308 and HL-07182 from the National Heart, Lung, and Blood Institute of the National Institutes of Health, Bethesda, Maryland; by the Attorney General of Indiana Public Health Trust; by the Roudebush Veterans Administration Medical Center; and by a Grant-in-Aid from the American Heart Association, Indiana Affiliate, Inc., Indianapolis, Indiana. |
Vol 111 - N° 6
P. 1113-1118 - juin 1986 Retour au numéro
Article précédent
- Transvenous catheter ablation of the His bundle in ventricular tachycardia
- Giuseppe Critelli, Marino Scherillo, Vittorio Monda, Cristoforo D'Ascia, Salvatore Musumeci, Anita Antignano
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- W.S. Seitz, M.B. McIlroy, H. Kline, J. Operschall, I.A. Kashani
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