Dietary-dependent carnitine deficiency as a causeof nonketotic hypoglycemia in an infant - 07/10/17
Abstract |
Recurrent episodes of hypoglycemia, prostration, vomiting, and hepatomegaly were observed in an infant fed a carnitine-free soy formula. The extremely low plasma and urinary carnitine concentrations, elevated plasma free fatty acids, disproportionately low plasma beta hydroxybutyrate, and elevated urinary dicarboxylic acids, in the presence of a fatty liver, suggested that carnitine deficiency was the basis for this child's metabolic disturbance. When the infant was fed an enriched carnitine diet, remarkable clinical, biochemical, and histologic improvement was observed. The possibility that carnitine may be an essential nutrient for some infants is raised by the findings in this patient.
Le texte complet de cet article est disponible en PDF.† | Supported by Clinical Research Grant from theNational Foundation-March of Dimes No. 6-239, Public Health Service Grant No. 5MO1 RR-95, from the General Clinical Research Centers Branch of the Division of Research Resources, National Institutes of Health, and BRSG, RR-05424. |
Vol 99 - N° 4
P. 551-556 - octobre 1981 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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